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Becoming ‘Greener’ with Light Microscopy

Sponsored by CoolLED, on 11 October 2023

Working in a laboratory, you can’t help but notice how everyday tasks can impact the environment – from reliance on single-use plastics to energy-hungry equipment. While this might seem unavoidable, sustainable options are becoming widely available. In fact, many technologies and initiatives now exist to support the scientific community on the journey towards sustainable laboratories.

Microscopy preprints – bioimage analysis tools

Posted by FocalPlane, on 6 October 2023

Here is a curated selection of preprints published recently. In this post, we focus specifically on new tools for bioimage analysis.

behind DeXtrusion: an automated pipeline to detect epithelial cell extrusion through machine learning

Posted by Alexis Villars, on 6 October 2023

The problem In animals, epithelial tissue covers most of our organs. In order to create the very intricate and complex shapes of these organs, these tissues are drastically remodelled during embryogenesis through growth and shape changes. Once they achieve these final shapes, they maintain their cell number in a dynamic equilibrium. Both of these mechanisms,

Featured image with Peggy Paschke

Posted by FocalPlane, on 29 September 2023

Our featured image is called Dictyostelium Trees on Fire and was acquired by Peggy Paschke. The image shows Dictyostelium discoideum cells stably expressing the cAMP sensor Flamindo2. Cells were imaged as 5×5 tile scan for 5 hours with a Nikon AXR (488 nm excitation) using a 4x air objective. Shown is a cropped part of

How to… Publish Images blog series

Posted by FocalPlane, on 27 September 2023

by Helena Jambor In biology, images document appearances or structures of animals, issues, or cells, and increasingly are a source of quantitative insights of biological processes. Many papers are published every single day with images (Lee, 2018).Not all of these images are truthful or insightful. Some images are manipulated to mislead audiences (Bik et al.,

Microscopy preprints – applications in biology

Posted by FocalPlane, on 22 September 2023

In this post, we share preprints that use microscopy tools to answer questions in biology.

The FocalPlane Network: joining and using the database

Posted by FocalPlane, on 20 September 2023

Our instructional videos take you step-by-step through the process of joining and using the FocalPlane Network. You can contact us at focalplane@biologists.com with any feedback on the Network. Joining the FocalPlane Network Using the FocalPlane Network

The FocalPlane Network: connecting the microscopy community

Posted by FocalPlane, on 20 September 2023

The FocalPlane Network is an international directory of researchers with expertise in microscopy. The goal of the Network is to facilitate promotion and networking, as well as assisting those seeking conference speakers, committee members, reviewers or collaborators. Membership is open to researchers in the microscopy community from all career stages, geographical locations or areas of

An interview with Zayra Garavito Aguilar

Posted by Mariana De Niz, on 19 September 2023

MiniBio: Prof. Zayra Garavito is a principal investigator at Universidad de los Andes, in the Department of Biological Sciences. She began her career in Colombia, where already at a young age she discovered her interest for processes and mechanisms of regeneration. She became a young investigator at the Institute of Science in Colombia, and later

An interview with Helen Spiers

Posted by Helen Zenner, on 18 September 2023

Citizen science is a fantastic way to engage the public with scientific research by getting them involved with real research projects. For scientists, the power of the crowd can help them overcome analysis bottlenecks that might otherwise slow the pace of their research. Martin Jones and Lucy Collinson, from the Crick Electron Microscopy Science Technology

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Microscopy-related articles from our journals

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples Development 2024 151: dev202307
filoVision – using deep learning and tip markers to automate filopodia analysis J Cell Sci 2024 137: jcs261274
C omputational tools for quantifying actin filament numbers, lengths, and bundling Biology Open 2024 13: bio.060267

Microscopy-related preprint highlights

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