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And the winner is...

Posted by , on 1 September 2023

We are delighted to announce that the winner of the 2023 FocalPlane image competition is Rebecca Simkin. Rebecca’s image, ‘Neuromuscular junctions’, depicts four NMJs in a lumbrical muscle, located in the hind paw of a wildtype mouse. A wholemount immunostaining was performed using 2H3 and SV2 antibodies to visualise lower motor neurons in green (specifically

Technology Highlights - Expansion Microscopy

Posted by , on 29 August 2023

Interview with Ana Agostinho and Steven Edwards, at the Advanced Light Microscopy facility at SciLifeLab in Sweden. We are today talking about Expansion Microscopy imaging. Please provide a short summary of this type of imaging and list some applications: Ana: My name is Ana Agostinho and I am a staff scientist at the Advanced Light

An interview with Federico Brown

Posted by , on 29 August 2023

MiniBio: MiniBio: Prof. Federico Brown is currently a principal investigator at Universidade de São Paulo in Brazil, where he focuses on evolutionary and developmental biology. Federico began his career in Ecuador, where he worked as an undergraduate in the lab of Prof. Eugenia del Pino. This is where he first found his passion for EvoDevo,

Microscopy preprints – bioimage analysis tools

Posted by , on 25 August 2023

Here is a curated selection of preprints published recently. In this post, we focus specifically on new tools for bioimage analysis.

Unveiling the Marvels of the First-Ever Gordon Research Conference on Volume Electron Microscopy - Capturing Subcellular Architecture from Organelles to Organisms -By Ana Correia and James Thompson

Posted by , on 24 August 2023

We delve into our captivating journey at the first Gordon Research Conference (GRC) on Volume Electron Microscopy (vEM) as early career scientists. Set against the backdrop of sunny Ventura, California, this conference brought together experts in the vEM field from all corners of the globe, creating an intellectual haven for learning, networking, and forging collaborations.

An interview with Mario Del Rosario

Posted by , on 22 August 2023

MiniBio: Dr. Mario Del Rosario is currently a postdoctoral scientist in the lab of Prof. Ricardo Henriques at Instituto Gulbenkian de Ciencias, in Oeiras, Portugal. Mario completed his undergraduate studies at Escuela Superior Politécnica del Litoral, where he studied for a BSc in Biology. He then did a Maters in Research in Biomedical Sciences at

Featured image with Beste Senem Değirmenci

Posted by , on 18 August 2023

Our featured image, ‘Bubbles of The Cell’, shows enlarged endosomal vesicles in HeLa S3 cells upon inhibition of PI(3,5)P2 activity. PI(3,5)P2 is a crucial phosphoinositide involved in the regulation of endosomal trafficking. Depletion of PI(3,5)P2 disrupts the transition from early to late endosomes, leading to the enlargement of endosomal vesicles. Imaged with Leica DMI8 SP8

An interview with Santiago Casado

Posted by , on 15 August 2023

MiniBio: Dr. Santiago Casado is a Chemical Physicist currently working as a Deputy division leader at the Facultad de Ciencia e Ingeniería en Alimentos y Biotecnología Research Department at Universidad Técnica de Ambato, in Ecuador. Dr. Casado studied his undergraduate degree in Physics in Universidad de Cantabria, in Santander, Spain. He then studied his PhD

Microscopy preprints – applications in cell and developmental biology

Posted by , on 11 August 2023

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools in cell biology and developmental biology.

An interview with Samira Vera

Posted by , on 8 August 2023

MiniBio: Samira is a PhD student in the lab of Mohammed Mostajo at University of California at Santa Cruz, in the USA, where she focuses on neurophysiology and in open science and open education. She started her career in Peru, where she completed her BSc in Genetics and Biotechnology at Universidad Nacional Mayor de San