Funded PhD position from Academy of Medical Sciences – Papagiannouli Lab, UK

This PhD project will systematically explore the function of squamous cyst cells in the Drosophila testis and how their internal structure facilitates communication with neighbouring germ cells and coordinates tissue-wide responses leading to sperm production. The Drosophila testis is a powerful system, as its simple morphology is combined with sufficient complexity and cellular conservation. Stem cells and differentiating cell types are well-characterised and can be easily traced, while phenotypes can be studied in vivo. To this end, you will use state-of-the-art Drosophila genetic and advanced protein-interaction techniques as well as high-resolution light and electron microscopy. Our findings will impact researchers in stem cell & developmental biology, regenerative medicine, disease modelling and translational research in the longer-term, by targeting the altered signalling networks in squamous cell carcinomas and creating novel therapeutics to treat human disease.
You will be part of a dynamic environment and vibrant PhD community at **Medway School of Pharmacy **and the Universities of Kent and Greenwich at Medway Campus. You will have access to fully operational fly and molecular lab, shared microscopy and proteomic facilities, and will work alongside our world-renowned collaborators with complementing expertise.

For information about the project contact Dr Fani Papagiannouli: f.papagiannouli-227@kent.ac.uk