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Embryonic dorsal root ganglia

Dorsal root ganglia are constituted of sensory neurons devoted to detect somatic features such as touch and pain. They transmit these peripheral informations to the central nervous system by targeting spinal cord interneurons. This image shows dorsal root ganglia projecting their roots to the spinal cord. The image is a color-depth coded immunostaining of the neurofilament Peripherin in a E13.5 murine embryo cleared with the SeeDB protocol. Images were acquired on a LSM710 confocal microscope and processed with Fiji. By Simon Desiderio

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Recent posts

Microscopy preprints – applications in cell biology

Posted by , on 12 August 2022

Here is a curated selection of preprints published recently. In this post, we focus specifically on preprints using microscopy tools in cell biology.

Affimers – small probes for big imaging experiments

Posted by , on 9 August 2022

Antibodies have been used to label proteins of interest since the 1970s. However, their large size (around 15 nm long for IgG) makes the penetration of dense structures within the cell a challenge and places the fluorophore away from the target protein. This latter issue, known as a ‘linkage error’, particularly impacts accuracy and precision

News digest

Posted by , on 5 August 2022

Here is a selection of interesting news, publications and discussions related to microscopy that happened in the last two weeks on Twitter and beyond. Talks, training and workshops: Registration is still open for the BNMI (Bridging the Nordic Microscopy Infrastructure) symposium in Iceland The 9th Electron Tomography Congress is happening in September in The Netherlands

Microscopy in Africa – an interview with Michael Reiche

Posted by , on 29 July 2022

We talk with Michael Reiche about the recently launched African Microscopy Inititiative and two other imaging-related programmes in Africa that he is overseeing

Microscopy preprints – new tool and techniques in imaging and image analysis

Posted by , on 29 July 2022

Here is a curated selection of preprints published recently. In this post, we focus specifically on preprints on tools and techniques.

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Updated on 28 July 2022