I am a cell and developmental biologist currently working as a post-doctoral research fellow in Clare Waterman’s group at National Institutes of Health, Bethesda USA. I am interested in the spatial organization and patterning of signaling components on the plasma membrane and how signaling dynamics regulate downstream cytoskeletal processes. I am currently looking at the bleb-based migration under low adhesion and high confinement in melanoma metastatic cells. I am curious about how metastatic cells remain polarized while moving under different extra-cellular matrix conditions? During my PhD, I worked under the mentorship of Thomas Lecuit in Marseille France and in collaboration with Satyajit Mayor in NCBS, Bangalore India to work on the interface of membrane organization of signaling components on the plasma membrane regulating mechanics during gastrulation. I was curious to understand molecular basis of germ-band extension, which is one of the key morphogenetic events during gastrulation. To understand this, I did quantitative measurements of receptor-ligand interactions on the plasma membrane by using fluorescence correlation spectroscopy (FCS) and reported activation of receptor by measuring receptor cluster formation in vivo. Apart from bench work I enjoy advocating for open science and use of preprints, work on STEM outreach activities and playing online games!!
Posted by Ankita Jha, on 1 January 2021I’ve always believed public outreach and education activities are vital to our role as scientists. While both are familiar concepts to many of us, often they are unappreciated as important parts of our scientific training and journey. This has become increasingly relevant during this year, where a rise in public mistrust and misunderstanding of the
With the help of ASCB outreach grant, this camp is organized for students (age group 10-15 years) where they receive a foldscope. The event is divided into multiple sessions where students cover topics like ecology, cell biology and crystal chemistry.
Date: 16 November 2020 — 5 December 2020