Using the Dragonfly Spinning Disk Confocal to Understand the Molecular Basis of Epigenetics

Sponsored by Andor, on 28 March 2022

Silviya Dimova: Uncovering the Epigenetic Role of PRC2 in the Meehan Laboratory Epigenetics is the study of transmissible modifications in gene expression that are not encrypted in the genomic DNA, and for this reason, are named (Epi)genetic – (Above)genetics.  Epigenetics is linked with chemical modifications to DNA or chromatin proteins. A common epigenetic modification is DNA

Overview of Microscopy Techniques: Confocal, Widefield, Transmitted Light and Deconvolution

Sponsored by Andor, on 30 November 2021

Microscopes are an essential tool for modern life science applications. From medical diagnostics (for example, identifying the source of an infection, or the severity of a tumour) to food analysis.  With such demand it is not surprising that in the last decade, there has been a boom in microscopy technologies allowing researchers to see beyond

Dragonfly: The Ideal Confocal System for Expansion Microscopy

Sponsored by Andor, on 30 August 2021

Challenges in Imaging Expanded Samples The resolution in light microscopy is limited by the diffraction limit of light, which means that structures that are closer than 200 nm apart cannot be distinguished unless researchers use Super-resolution techniques. An alternative approach to super-resolution methods was developed by Edward Boyden’s laboratory at MIT in 2015 [1]. Instead of increasing