Afonso Mendes

I'm a biologist with a passion for viruses and host-pathogen interactions. I study the dynamic architecture of viral and host protein complexes and how they influence viral replication. My approach is a mix of super-resolution microscopy, machine-learning, optoelectronics, and additive manufacturing.

Structural Repetition Detector (SReD): quantitative mapping of molecular complexes through microscopy

Posted by Afonso Mendes, on 23 September 2024

Unbiased, multi-dimensional, multi-scale and GPU-accelerated analysis of structural patterns across all microscopy modalities From biomolecules to larger assemblies and cellular architectures, molecular structures govern biological processes. Identifying these repetitive patterns is essential to understand their functions and the underlying biological mechanisms. While microscopy offers molecular-level detail, manually detecting structural motifs is labor-intensive, susceptible to bias,