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FocalPlane

Posts from the FocalPlane team

About FocalPlane

Microscopy background: Optical System Development, Image Analysis, Probe Development

Posts by FocalPlane

Register for Journal of Cell Science Meeting on Imaging Cell Dynamics

Posted by , on 15 September 2025

Registration is open for Journal of Cell Science Meeting on Imaging Cell Dynamics. The meeting will bring together experts working at the interface between cell biology and imaging, with a focus on researchers who use advanced light and electron microscopy approaches, and novel image analysis tools.
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Featured image with Mathieu Preußner

Posted by , on 12 September 2025

Our featured image, acquired by Mathieu Preußner, is a lateral view of the overlying gill arches in 1-month-old Danio rerio expressing endothelial kdrl:mCherry. Clarity-based tissue clearing of the sample enabled comprehensive image acquisition using a Nikon Ti spinning disk system. In ImageJ, the hyperstack was modified using a temporally colour-coded lookup table.
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JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42

Posted by , on 10 September 2025

In our latest JCS snapshot, we hear from Adam Rochussen who, together with Gillian Griffiths and Claire Ma, discovered that cytotoxic T lymphocytes are able to adapt to the loss of the key polarity factor Cdc42. In this snapshot, Adam takes us through the key findings from their research.
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Microscopy preprints - new tools and techniques in imaging

Posted by , on 5 September 2025

Here is a curated selection of preprints posted recently on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!
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Featured image with David Grainger

Posted by , on 29 August 2025

Our featured image, acquired by David Grainger, is a colour-coded depth projection of the blood endothelial cells of the E14.5 mouse embryonic thymus and surrounding structures. A 200 μm-thick vibratome section was immunostained for endomucin and imaged on a Zeiss LSM980 confocal microscope and depth-encoded using a rainbow LUT before performing a maximum intensity projection. 
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Recent events by FocalPlane

IMC21

Location: Liverpool, UK

Date: 30 August 2026 — 4 September 2026

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Microscopy of Oxidation 12

Abstract submission deadline: 30th September 2025

Location: ,

Date: 18 May 2026 — 20 May 2026

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Journal of Cell Science – Imaging Cell Dynamics

This meeting will provide a unique opportunity to bring together experts working at the interface between cell biology and imaging, with a focus on researchers who use advanced light and electron microscopy approaches, and novel image analysis tools.

Location: Montanyà Hotel, Catalonia, Spain

Date: 11 May 2026 — 14 May 2026

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