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FocalPlane

Posts from the FocalPlane team

About FocalPlane

Microscopy background: Optical System Development, Image Analysis, Probe Development

Posts by FocalPlane

JCS snapshot - Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation

Posted by , on 12 January 2026

In our latest JCS snapshot we hear from Anne Müsch, who, together with David Cohen and Francisco Lázaro-Diéguez, discovered that bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation.

Microscopy preprints – new tools and techniques in imaging

Posted by , on 9 January 2026

Here is a curated selection of preprints posted recently on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!

Imaging spotlight: Lock-in-SIM

Posted by , on 8 January 2026

In this paper highlight from Wenjie Liu and colleagues, we learn about Lock-in-SIM, a new methodology for structured illumination microscopy.

Featured image with Christina Daly

Posted by , on 6 January 2026

Our featured image, acquired by Christina Daly, is of an E9.5 murine neural tube. The embryo was fixed in 4% Paraformaldehyde, embedded in agarose, and vibratome-sectioned at 100 mm thickness. The sections were stained with for F-actin with phalloidin and imaged on a Nikon A1R confocal.

Microscopy preprints: bioimage analysis

Posted by , on 29 December 2025

Here is a curated selection of preprints published (or updated) recently. In this post we focus specifically on bioimage analysis and data management.

Recent events by FocalPlane

2nd UK Biomolecular Condensate Network Conference

The 2nd meeting of the national Network will take place 8-10 December at De Vere Horsley estate in Surrey.

Location: DeVere Horsley Estate, Surrey, UK

Date: 8 December 2027 — 10 December 2027

EMBO | EMBL Symposium Cell biology of the nucleus

The goal of this conference is to showcase the cell biological mechanisms that define the nucleus as an organelle.

Location: Heidelberg, Germany and Virtual

Date: 16 November 2027 — 19 November 2027

RBSCDB Autumn meeting on Cell Migration

The 2026 Autumn RBSCDB meeting will focus on Cell Migration.

Location: Charleroi, Belgium

Date: 13 November 2027