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FocalPlane

Posts from the FocalPlane team

About FocalPlane

Microscopy background: Optical System Development, Image Analysis, Probe Development

Posts by FocalPlane

JCS snapshot - TMEM184B modulates endolysosomal acidification via the vesicular proton pump

Posted by , on 17 September 2025

In our latest JCS snapshot we hear from Elizabeth Wright, who, together with Martha Bhattacharya and colleagues, discovered that TMEM184B modulates endolysosomal acidification via the vesicular proton pump. In this snapshot, Elizabeth takes us through the key findings from their research.
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FocalPlane features... membrane trafficking

Posted by , on 16 September 2025

Registration is open for our upcoming mini-symposium together with the popular Membrane Trafficking webinar series, organised by Francesca Bottanelli, Felix Campelo and Ishier Raote. Our event, on Thursday 25 September, will be a celebration of the membrane trafficking community.
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Register for Journal of Cell Science Meeting on Imaging Cell Dynamics

Posted by , on 15 September 2025

Registration is open for Journal of Cell Science Meeting on Imaging Cell Dynamics. The meeting will bring together experts working at the interface between cell biology and imaging, with a focus on researchers who use advanced light and electron microscopy approaches, and novel image analysis tools.
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Featured image with Mathieu Preußner

Posted by , on 12 September 2025

Our featured image, acquired by Mathieu Preußner, is a lateral view of the overlying gill arches in 1-month-old Danio rerio expressing endothelial kdrl:mCherry. Clarity-based tissue clearing of the sample enabled comprehensive image acquisition using a Nikon Ti spinning disk system. In ImageJ, the hyperstack was modified using a temporally colour-coded lookup table.
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JCS snapshot - Cytotoxic T lymphocytes adapt to the loss of Cdc42

Posted by , on 10 September 2025

In our latest JCS snapshot, we hear from Adam Rochussen who, together with Gillian Griffiths and Claire Ma, discovered that cytotoxic T lymphocytes are able to adapt to the loss of the key polarity factor Cdc42. In this snapshot, Adam takes us through the key findings from their research.
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Recent events by FocalPlane

IMC21

Location: Liverpool, UK

Date: 30 August 2026 — 4 September 2026

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Microscopy of Oxidation 12

Abstract submission deadline: 30th September 2025

Location: ,

Date: 18 May 2026 — 20 May 2026

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Electron crystallography workshop 2026

Location: Venice, Italy

Date: 11 May 2026 — 13 May 2026

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