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FocalPlane

Posts from the FocalPlane team

About FocalPlane

Microscopy background: Optical System Development, Image Analysis, Probe Development

Posts by FocalPlane

Featured image with Julia Zheku

Posted by , on 13 March 2026

Our featured image, acquired by Julia Zheku, depicts a maize (corn) cross section, with a developing nodal root dynamically breaking through the basal stem node which is typically found below the soil surface. Such a root is not visible while sectioning, making this a beautiful, yet lucky, image. The section was prepared by mounting the

Imaging spotlight: Altair-LSFM

Posted by , on 9 March 2026

In this paper highlight from Kevin Dean and colleagues, we learn about Altair-LSFM, a light-sheet fluorescence microscope that they designed so it can be built and operated in biology labs without needing a full-time optical engineer.

Microscopy preprints - applications in biology

Posted by , on 9 March 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.

JCS snapshot: Redefining colocalization analysis with a novel phasor mixing coefficient

Posted by , on 6 March 2026

In our latest JCS snapshot we hear from Owen Puls, who together with Teng-Leong Chew and team define a new strategy for quantifying biological association that leverages multispectral imaging and phasor analysis, termed the phasor mixing coefficient (PMC). In this snapshot, Owen takes us through the key findings from their research.

Imaging spotlight: the axonal membrane-associated periodic skeleton

Posted by , on 5 March 2026

In this paper highlight, Nick Boyer takes us through the key results and imaging techniques that they used in their research dissecting the axonal membrane-associated periodic skeleton with Rohan Sharma, Christophe Leterrier, Subhojit Roy and colleagues.

Recent events by FocalPlane

Processing and Analysis of Biological Images

Location: Brno, Czech Republic

Date: 1 December 2026 — 4 December 2026

Image analysis for Correlative Light and Electron Microscopy (CLEM)

Location: London, United Kingdom

Date: 30 November 2026 — 4 December 2026

6th Day of Intravital Microscopy

Location: Bonn, North Rhine Westfalia, Germany

Date: 23 November 2026 — 24 November 2026