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FocalPlane

Posts from the FocalPlane team

About FocalPlane

Microscopy background: Optical System Development, Image Analysis, Probe Development

Posts by FocalPlane

Featured image with David Grainger

Posted by , on 29 August 2025

Our featured image, acquired by David Grainger, is a colour-coded depth projection of the blood endothelial cells of the E14.5 mouse embryonic thymus and surrounding structures. A 200 μm-thick vibratome section was immunostained for endomucin and imaged on a Zeiss LSM980 confocal microscope and depth-encoded using a rainbow LUT before performing a maximum intensity projection. 

Microscopy preprints - bioimage analysis

Posted by , on 22 August 2025

Here is a curated selection of preprints published recently. In this post, we focus specifically on bioimage analysis and data management.

FocalPlane features... meets preLights

Posted by , on 20 August 2025

For our second collaborative FocalPlane features… webinar we have teamed up with preLights, our sister community site. This webinar will be hosted by Felipe Del Valle Batalla (University of Edinburgh, UK) and Vibha Singh (Princess Margaret Cancer Research Tower (UHN), Canada), two members of the preLights community (known as preLighters), who have selected two recent

Featured image with Ludovica Altieri

Posted by , on 15 August 2025

Our featured image, acquired by Ludovica Altieri, shows murine primary cortical neurons developing interconnections. The cells are stained for neuronal tubulin (TUJI antibody, cyan) and DNA (DAPI, blue). Cultures were prepared by dissecting cortices from mouse embryos (E18), then mechanically dissociating single cells for plating. Explanted primary neurons placed in culture regress several stages back,

Microscopy preprints - applications in biology

Posted by , on 12 August 2025

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.

Recent events by FocalPlane

2nd UK Biomolecular Condensate Network Conference

The 2nd meeting of the national Network will take place 8-10 December at De Vere Horsley estate in Surrey.

Location: DeVere Horsley Estate, Surrey, UK

Date: 8 December 2027 — 10 December 2027

EMBO | EMBL Symposium Cell biology of the nucleus

The goal of this conference is to showcase the cell biological mechanisms that define the nucleus as an organelle.

Location: Heidelberg, Germany and Virtual

Date: 16 November 2027 — 19 November 2027

RBSCDB Autumn meeting on Cell Migration

The 2026 Autumn RBSCDB meeting will focus on Cell Migration.

Location: Charleroi, Belgium

Date: 13 November 2027