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FocalPlane

Posts from the FocalPlane team

About FocalPlane

Microscopy background: Optical System Development, Image Analysis, Probe Development

Posts by FocalPlane

JCS snapshot: Suppressing microtubule detyrosination augments AAV2 endosomal escape & gene delivery

Posted by , on 19 February 2026

In our latest JCS snapshot we hear from Shefali Tripathi, who, together with Nitin Mohan, Giridhara Jayandharan and team, found that suppressing microtubule detyrosination augments adeno-associated virus 2 endosomal escape and gene delivery.

Featured image with Jan Martinek

Posted by , on 13 February 2026

Our featured image is a spinning disk fluorescence micrograph, acquired by Jan Martinek, showing an Arabidopsis thaliana root that formed a spiral on a forgotten Petri dish lying flat on the bench. In this orientation, the root cannot grow downward gravitropically, so it keeps turning.

JCS snapshot: RNP1A regulates cell shape in Dictyostelium amoebas

Posted by , on 12 February 2026

In our latest JCS snapshot we hear from Mark Jacob, who, together with Yinan Liu, Douglas Robinson and team, found that the RNA-binding protein RNP1A regulates cell shape in Dictyostelium amoebas. In this snapshot, Mark takes us through the key findings from their research.

Imaging spotlight - How to divide without a ring: a mechanical ratchet drives unilateral cytokinesis

Posted by , on 10 February 2026

In this paper highlight, Jan Brugués and Alison Kickuth discuss the microscopy and microrheology techniques that they used in their research dissecting the mechanics of cytokinesis.

Workshop report: EMBO Course on Image Processing in Cryo-EM

Posted by , on 9 February 2026

Freya Cardozo shares her workshop report from the EMBO course on Imaging Processing in Cryo-EM. Freya's attendance was supported with a JCS-FocalPlane Training Grant.

Recent events by FocalPlane

Processing and Analysis of Biological Images

Location: Brno, Czech Republic

Date: 1 December 2026 — 4 December 2026

Image analysis for Correlative Light and Electron Microscopy (CLEM)

Location: London, United Kingdom

Date: 30 November 2026 — 4 December 2026

Crick BioImage Analysis Symposium 2026 (CBIAS 2026)

Abstract submission deadline: 31st August 2026

Location: London, United Kingdom

Date: 23 November 2026 — 24 November 2026