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Joachim Goedhart

Our lab develops, improves and compares genetically encoded fluorescent probes, that are inspired by Green Fluorescent Protein (GFP). We use the most optimal fluorescent proteins to generate biosensors for quantitative functional imaging with the overarching goal to unravel (G protein) signaling networks in time and space in cells and tissues. The majority of the genetically encoded tools that we have developped are shared through addgene. To simplify the quantification and presentation of data, we develop analysis tools and data visualization apps that are gathered here.

About Joachim Goedhart

Scientific field: Cell biology, Molecular biology, Biophysics, Biochemistry, Biotechnology

Microscopy background: Probe Development, Image Analysis

Posts by Joachim Goedhart

60 years of Fluorescent Proteins

Posted by , on 4 October 2022

In talks about fluorescent proteins I usually include a timeline of events related to Green Fluorescent Protein (GFP). The timeline highlights some of the key moments in the history of fluorescent protein discovery and engineering. I am generally fond of timelines, since they provide a way to pay tribute to the pioneers, and other researchers

My history with GFP (and other members of the family)

Posted by , on 7 July 2020

I first crossed paths with green fluorescent protein (GFP) while doing an internship in 1996 at the Max Planck Institute in Göttingen. I was chemically labeling epidermal growth factor (EGF) with the fluorescent dyes Cy3 and Cy5 to study growth-factor signaling. Two post-docs were discussing the use of GFP as an alternative fluorescent tag and