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FocalPlane

Posts from the FocalPlane team

About FocalPlane

Microscopy background: Optical System Development, Image Analysis, Probe Development

Posts by FocalPlane

Featured image with Manomay Pawar

Posted by , on 20 July 2026

Our featured image, acquired by Manomay Pawar, depicts MDA-MB-231 triple negative breast cancer cells treated with drug Bemcentinib (R428), a small molecule inhibitor of AXL (a receptor tyrosine kinase) and labelled with phalloidin (actin;green), anti-Paxillin antibody to mark focal adhesions (magenta) and DAPI (DNA;yellow). The white coloured puncta represent colocalisation of paxillin with the ends
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Microscopy preprints: applications in biology

Posted by , on 15 July 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Imaging spotlight: VLab4Mic

Posted by , on 7 July 2026

In this preprint highlight, Damián Martínez, Bruno M. Saraiva, Mario Del Rosario, Ricardo Henriques introduce VLab4Mic, an open-source simulation platform that allows researchers to optimise microscopy experiments before performing them.
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Journal of Cell Science Special Issue: Cell Biology of the Nucleus

Posted by , on 6 July 2026

Journal of Cell Science’s special issue on the cell biology of the nucleus is now complete. In their Editorial, Megan King and Abby Buchwalter discuss the themes of the special issue, including the connections between the nucleus and cytoskeleton, nuclear mechanics, nuclear lipids, the nuclear pore complex and nuclear transport, the nuclear lamina, chromatin and
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Featured image with Joan Roncero Carol

Posted by , on 3 July 2026

Our featured image, acquired by Joan Roncero Carol, shows two mouse preimplantation blastocysts at E4.5 showing immunofluorescence staining against LAMP1 to visualize lysosomal distribution at this developmental stage, together with phalloidin staining to clearly outline cell membranes.
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Recent events by FocalPlane

2nd UK Biomolecular Condensate Network Conference

The 2nd meeting of the national Network will take place 8-10 December at De Vere Horsley estate in Surrey.

Location: DeVere Horsley Estate, Surrey, UK

Date: 8 December 2027 — 10 December 2027

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EMBO | EMBL Symposium Cell biology of the nucleus

The goal of this conference is to showcase the cell biological mechanisms that define the nucleus as an organelle.

Location: Heidelberg, Germany and Virtual

Date: 16 November 2027 — 19 November 2027

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RBSCDB Autumn meeting on Cell Migration

The 2026 Autumn RBSCDB meeting will focus on Cell Migration.

Location: Charleroi, Belgium

Date: 13 November 2027

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