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FocalPlane

Posts from the FocalPlane team

About FocalPlane

Microscopy background: Optical System Development, Image Analysis, Probe Development

Posts by FocalPlane

JCS snapshot: A ULK1–MTFR1L feedback loop links mitochondrial fission, mitophagy and apoptosis

Posted by , on 22 July 2026

In our latest JCS snapshot we hear from Riccardo Babic, Leon Lucya and Christoph Reiter, who, together with Claudine Kraft and team, identified a ULK1–MTFR1L feedback loop that links mitochondrial fission, mitophagy and apoptosis.
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Pearling and directed trafficking as determinants of mitochondrial genome organization and network architecture

Posted by , on 21 July 2026

In this highlight, we hear from Juan C. Landoni, who discusses his recent work uncovering how mitochondria distribute their genome through pearling (Landoni et al. 2026, Science), and the key role of mitochondrial trafficking in maintaining new material dissemination and network architecture (Winter, Landoni et al. 2026, JCB).
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Featured image with Manomay Pawar

Posted by , on 20 July 2026

Our featured image, acquired by Manomay Pawar, depicts MDA-MB-231 triple negative breast cancer cells treated with drug Bemcentinib (R428), a small molecule inhibitor of AXL (a receptor tyrosine kinase) and labelled with phalloidin (actin;green), anti-Paxillin antibody to mark focal adhesions (magenta) and DAPI (DNA;yellow). The white coloured puncta represent colocalisation of paxillin with the ends
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Microscopy preprints: applications in biology

Posted by , on 15 July 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Imaging spotlight: VLab4Mic

Posted by , on 7 July 2026

In this preprint highlight, Damián Martínez, Bruno M. Saraiva, Mario Del Rosario, Ricardo Henriques introduce VLab4Mic, an open-source simulation platform that allows researchers to optimise microscopy experiments before performing them.
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Recent events by FocalPlane

2nd UK Biomolecular Condensate Network Conference

The 2nd meeting of the national Network will take place 8-10 December at De Vere Horsley estate in Surrey.

Location: DeVere Horsley Estate, Surrey, UK

Date: 8 December 2027 — 10 December 2027

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EMBO | EMBL Symposium Cell biology of the nucleus

The goal of this conference is to showcase the cell biological mechanisms that define the nucleus as an organelle.

Location: Heidelberg, Germany and Virtual

Date: 16 November 2027 — 19 November 2027

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RBSCDB Autumn meeting on Cell Migration

The 2026 Autumn RBSCDB meeting will focus on Cell Migration.

Location: Charleroi, Belgium

Date: 13 November 2027

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