Expansion Microscopy

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[FRANCE-BIOIMAGING] Join the SFBS 2026 workshop & symposium!

Posted by Marine Beraud, on 9 April 2026

Registrations are now open for the Sino-French BioImaging Symposium 2026 (SFBS 2026), which will take place in Bordeaux (France) from October 14 to 21, 2026. This event is organized within the framework of the International Research Network (IRN) BioImage between France and China, aiming to strengthen scientific exchanges between the French and Chinese bioimaging communities

Spider-like neurons finding their way: signposts for multipolar migration in the developing brain

Posted by Jaakko Lehtimäki, on 11 March 2026

Developing neurons travel large distances and orchestrate into precise layers to enable functional wiring of the brain. Within this unique tissue environment, many neurons use their neighbors like railway tracks, navigating in a directed manner toward their correct layer. However, this is not always the case. Multipolar migration, where cells extend multiple protrusions and display

Workshop report: CSHL Quantitative Imaging (QI): From Acquisition to Analysis

Posted by FocalPlane, on 4 March 2026

Estefania Sanchez-Vasquez shares her workshop report from the CSHL course on Quantitative Imaging (QI): From Acquisition to Analysis. Estefania’s attendance was supported by a JCS-FocalPlane Training Grant.

Microscopy preprints – applications in biology

Posted by FocalPlane, on 23 January 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.

Imaging spotlight: U-ExM atlas of microbial eukaryotes

Posted by FocalPlane, on 20 January 2026

In this paper highlight from Hiral Shah and colleagues, we learn about their ultrastructure expansion microscopy (U-ExM) atlas of over 200 cultured planktonic eukaryotes. This post includes technical advice for ExM users and highlights the open-access resource that they have generated for cytoskeleton or marine microorganism aficionados (and microscopy sciart lovers!)

Featured image with Md Hashim Reza

Posted by FocalPlane, on 22 November 2024

Our featured image, prepared by Md Hashim Reza, is an Andy Warhol-inspired illustration of a Candida albicans cell, post-expansion and labelled with BodipyTR, highlighting features of internal membrane organisation.

FocalPlane features... Imaging Cell Architecture and Dynamics with Journal of Cell Science

Posted by FocalPlane, on 15 November 2024

Our latest FocalPlane features… webinar was a celebration of the research in Journal of Cell Science’s Special Issue: Imaging Cell Architecture and Dynamics. Our Guest Editors Lucy Collinson and Guillaume Jacquemet hosted the webinar with talks from Md Hashim Reza, Melanie Rug and Vikas Tillu.

Journal of Cell Science Special Issue: Imaging Cell Architecture and Dynamics

Posted by Helen Zenner, on 5 November 2024

Journal of Cell Science’s Special Issue on Imaging Cell Architecture and Dynamics is now complete. The original research in this Issue, guest edited by Lucy Collinson and Guillaume Jacquemet, covers a diverse range of imaging methodologies including CLEM, super-resolution imaging, volume EM, high-throughput imaging, FRET, expansion microscopy, mesoscopy and immuno-SEM, as well as showcasing new

FocalPlane features... Imaging Cell Architecture and Dynamics with Journal of Cell Science

Posted by FocalPlane, on 17 October 2024

Our November webinar is a celebration of Journal of Cell Science’s Special Issue: Imaging Cell Architecture and Dynamics. Our Guest Editors, Lucy Collinson and Guillaume Jacquemet, have invited the authors of three of the papers published in this issue to present their research. View the ‘Special Issue: Imaging Cell Architecture and Dynamics’ here. Thursday 14

Featured image with Ciarán Butler Hallissey

Posted by FocalPlane, on 13 September 2024

Our featured image, acquired by Ciarán Butler Hallissey, is a maximum-intensity projection of rat hippocampal neurons processed with ultrastructure expansion microscopy (U-ExM) and captured with a spinning disk confocal microscope. Find out more about the image and Ciarán’s research below. More about the image: Expansion microscopy physically increases the size of your sample to improve

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Microscopy-related articles from our journals

Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface J Cell Sci 2025 138: jcs264154
The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential Development 2025 152: dev204661
The short isoform of Tango1 is dispensable for zebrafish survival but is required for skeletal patterning and integrity Biology Open 2025 14: bio062117

Microscopy-related preprint highlights

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Microscopy-related articles from our journals

Microscopy-related preprint highlights

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