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Highlighting signalling biosensors 1.

Posted by , on 16 January 2025

Why there is interest in signalling biosensors, considerations for using biosensors, and the original biosensor, GFP. Why write about signalling biosensors? In my first postdoctoral position, I was introduced to the concept of endosomal signalling- a way for receptor signalling outcomes to be changed by delivering a signal to different regions of the cell. I
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Probes 101 – How to choose a fluorescent probe for your imaging experiment

Posted by , on 14 December 2024

Fluorescence microscopy is a powerful tool for the visualization of the intricate biological processes occurring within biological organisms. Just like you can make important pieces of information pop up in their notes using colorful highlighters, biologists have at hand a large toolkit of “highlighters” to make their favorite targets stand out in the complex cellular
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SAM for Bioimage Analysis: A Comprehensive Guide

Posted by , on 10 December 2024

Image segmentation has always been a cornerstone of image analysis, and in bioimage analysis, its significance cannot be overstated. Precise segmentation of regions of interest is crucial for downstream analysis, yet the inherent complexity of biological data makes this task particularly challenging. While numerous segmentation methods exist, the field has long sought a generalist model
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Teaching co-localisation analysis from lecture to leisure

Posted by , on 20 October 2024

The origin There was one thing I was always skeptical about: colocalization analysis. When I started out as a BioImage Analyst, it was one of the first things I had to help users with in the BIOP at EPFL. I started learning more about it (and still continue to do so), tried with my own
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FocalPlane features... data management

Posted by , on 23 September 2024

The fourth webinar in the latest series of FocalPlane features… was on data management. Caterina Strambio De Castillia introduced us to the topic of research data management, while Tom discussed how to use OMERO from the perspective of a group leader, a microscopist and an image analyst. We wrapped up the webinar with a short
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MicroList and FocalPlane join forces

Posted by , on 2 September 2024

MicroList’s database of resources are now available on FocalPlane. The resources, which have been created by the global imaging community, are presented as cards that are divided into community resources, education resources and tools. The database is fully searchable using our search bar or can be filtered using a variety of categories.
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DL4MicEverywhere - Overcoming reproducibility challenges in deep learning microscopy imaging

Posted by , on 29 July 2024

DL4MicEverywhere is out! Learn about it and how you can apply deep learning workflows on microscopy imaging in reproducible research and in a user-friendly manner across different systems.
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Prompt Engineering in Bio-image Analysis

Posted by , on 18 July 2024

Prompt engineering and its importance Communication is key. This saying is not only true in day-to-day life, but also when interacting with Generative Artificial Intelligence, a system able to generate text, images or other output types in response to prompts. In prompt engineering, we use natural language to describe the task that a Large Language
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How to write a bug report

Posted by , on 3 April 2024

Imagine you try out a software tool for the analysis of your data and for some reason it is not working in the way you expected. Neither the user documentation, nor forums like image.sc or stack overflow can provide answers. Then it is likely that you either found a bug in the software tool or
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FocalPlane features... microscopy-based outreach

Posted by , on 11 March 2024

The first webinar of our new series of FocalPlane features... focussed on microscopy-based outreach. We hosted fantastic talks from Paola Moreno-Roman from Foldscope Instruments and Martin Jones from The Francis Crick Institute and we share the recordings here.
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