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Highlighting signalling biosensors 1.

Posted by , on 16 January 2025

Why there is interest in signalling biosensors, considerations for using biosensors, and the original biosensor, GFP. Why write about signalling biosensors? In my first postdoctoral position, I was introduced to the concept of endosomal signalling- a way for receptor signalling outcomes to be changed by delivering a signal to different regions of the cell. I
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An interview with Lina El Hajji

Posted by , on 9 January 2025

Lina was one of the three-minute talk presenters at our science communication event, SciCommConnect. At the event, which we co-hosted with the Node and preLights, we were treated to fantastic talks on a range of topics. Lina has kindly allowed us to share her presentation and we caught up with Lina to learn more about
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Probes 101 – How to choose a fluorescent probe for your imaging experiment

Posted by , on 14 December 2024

Fluorescence microscopy is a powerful tool for the visualization of the intricate biological processes occurring within biological organisms. Just like you can make important pieces of information pop up in their notes using colorful highlighters, biologists have at hand a large toolkit of “highlighters” to make their favorite targets stand out in the complex cellular
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FocalPlane features... Imaging Cell Architecture and Dynamics with Journal of Cell Science

Posted by , on 15 November 2024

Our latest FocalPlane features… webinar was a celebration of the research in Journal of Cell Science’s Special Issue: Imaging Cell Architecture and Dynamics. Our Guest Editors Lucy Collinson and Guillaume Jacquemet hosted the webinar with talks from Md Hashim Reza, Melanie Rug and Vikas Tillu.
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Advantages of LED Illumination for Neuroscience Research

Sponsored by CoolLED, on 26 September 2024

LED microscopy illumination has disrupted traditional approaches to high-speed imaging and optogenetic stimulation for neuroscience, and the CoolLED Support Team are available to help researchers understand which filters, light sources and other components are right for each individual setup.
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FocalPlane features... data management

Posted by , on 23 September 2024

The fourth webinar in the latest series of FocalPlane features… was on data management. Caterina Strambio De Castillia introduced us to the topic of research data management, while Tom discussed how to use OMERO from the perspective of a group leader, a microscopist and an image analyst. We wrapped up the webinar with a short
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MicroList and FocalPlane join forces

Posted by , on 2 September 2024

MicroList’s database of resources are now available on FocalPlane. The resources, which have been created by the global imaging community, are presented as cards that are divided into community resources, education resources and tools. The database is fully searchable using our search bar or can be filtered using a variety of categories.
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DL4MicEverywhere - Overcoming reproducibility challenges in deep learning microscopy imaging

Posted by , on 29 July 2024

DL4MicEverywhere is out! Learn about it and how you can apply deep learning workflows on microscopy imaging in reproducible research and in a user-friendly manner across different systems.
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A general strategy to develop fluorogenic polymethine dyes for bioimaging

Posted by , on 6 December 2023

by Annabell Martin and Pablo Rivera-Fuentes. Fluorescence imaging is an invaluable tool to study biological processes and further progress depends on the development of novel advanced fluorescent probes. Excitingly, using polymethines as a scaffold for fluorogenic dyes, we have opened up a lot of new avenues for bioimaging.
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Working smarter with LEDs and optical filters for widefield fluorescence

Sponsored by CoolLED, on 13 September 2023

Optical filters can make or break a fluorescence microscopy experiment. For widefield fluorescence, they also have the potential to unlock breakthroughs in high-speed, high-contrast imaging when used alongside multi-channel LED illumination systems. There are thousands of filters and dichroic mirrors to choose from, with the selection depending on the fluorophore(s) and light source. While imaging
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