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Exploring the Microcosmos through Foldscope-Frugal Science Microscopy in Focus

Posted by Aarushi Verma, on 18 July 2025

The third annual iteration of the Lodha Genius Programme at Ashoka University, Sonepat, featured a month-long workshop series for students of grades 9 and 10, introducing them to the intricate diversity of the microscopic world through the use of a frugal science innovation—the Foldscope. Much like the initiative described in this article on IndiaBioscience, this

Event carbon calculator

Posted by Teodora Andreea Rînciog, on 30 June 2025

I am excited to announce the release of our event carbon calculator, our latest resource to support the creation of sustainable events. Estimate your event’s carbon footprint in five minute or less. Our event carbon calculator provides insights into the main drivers of your meeting’s greenhouse gas emissions, offers reduction scenarios to test and provides

Annotating Images in Cellpose

Posted by Lea Kabjesz, on 5 June 2025

In this blog post, I’ll show you how to manually annotate cells in 2D and 3D images using the Cellpose Graphical User Interface (GUI). Manual annotation is a key step in many bioimage analysis workflows. It allows you to create labeled data that can serve as a reference for evaluating segmentation quality – or even

Highlighting signalling biosensors 1.

Posted by Greg Redpath, on 16 January 2025

Why there is interest in signalling biosensors, considerations for using biosensors, and the original biosensor, GFP. Why write about signalling biosensors? In my first postdoctoral position, I was introduced to the concept of endosomal signalling- a way for receptor signalling outcomes to be changed by delivering a signal to different regions of the cell. I

An interview with Lina El Hajji

Posted by FocalPlane, on 9 January 2025

Lina was one of the three-minute talk presenters at our science communication event, SciCommConnect. At the event, which we co-hosted with the Node and preLights, we were treated to fantastic talks on a range of topics. Lina has kindly allowed us to share her presentation and we caught up with Lina to learn more about

Probes 101 – How to choose a fluorescent probe for your imaging experiment

Posted by Lina El Hajji, on 14 December 2024

Fluorescence microscopy is a powerful tool for the visualization of the intricate biological processes occurring within biological organisms. Just like you can make important pieces of information pop up in their notes using colorful highlighters, biologists have at hand a large toolkit of “highlighters” to make their favorite targets stand out in the complex cellular

FocalPlane features... Imaging Cell Architecture and Dynamics with Journal of Cell Science

Posted by FocalPlane, on 15 November 2024

Our latest FocalPlane features… webinar was a celebration of the research in Journal of Cell Science’s Special Issue: Imaging Cell Architecture and Dynamics. Our Guest Editors Lucy Collinson and Guillaume Jacquemet hosted the webinar with talks from Md Hashim Reza, Melanie Rug and Vikas Tillu.

Advantages of LED Illumination for Neuroscience Research

Sponsored by CoolLED, on 26 September 2024

LED microscopy illumination has disrupted traditional approaches to high-speed imaging and optogenetic stimulation for neuroscience, and the CoolLED Support Team are available to help researchers understand which filters, light sources and other components are right for each individual setup.

Structural Repetition Detector (SReD): quantitative mapping of molecular complexes through microscopy

Posted by Afonso Mendes, on 23 September 2024

Unbiased, multi-dimensional, multi-scale and GPU-accelerated analysis of structural patterns across all microscopy modalities From biomolecules to larger assemblies and cellular architectures, molecular structures govern biological processes. Identifying these repetitive patterns is essential to understand their functions and the underlying biological mechanisms. While microscopy offers molecular-level detail, manually detecting structural motifs is labor-intensive, susceptible to bias,

FocalPlane features... data management

Posted by FocalPlane, on 23 September 2024

The fourth webinar in the latest series of FocalPlane features… was on data management. Caterina Strambio De Castillia introduced us to the topic of research data management, while Tom discussed how to use OMERO from the perspective of a group leader, a microscopist and an image analyst. We wrapped up the webinar with a short

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Microscopy-related articles from our journals

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples Development 2024 151: dev202307
filoVision – using deep learning and tip markers to automate filopodia analysis J Cell Sci 2024 137: jcs261274
C omputational tools for quantifying actin filament numbers, lengths, and bundling Biology Open 2024 13: bio.060267

Microscopy-related preprint highlights

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