Default - FocalPlane

Displaying posts in the category: Default

Bridging AI and Super-Resolution Microscopy: Highlights from the AI4Life Workshop & Hackathon at SMLMS 2024

Posted by Estibaliz Gómez-de-Mariscal, on 22 July 2025

In the days leading up to the Single Molecule Localization Microscopy Symposium (SMLMS) 2024, AI4Life hosted the Pre-symposium AI4Life Workshop & Hackathon: Trends in AI for Super-Resolution Microscopy at the Instituto Gulbenkian de Ciência (IGC) (now Gulbenkian Institute for Molecular Medicine (GIMM)) in Portugal. The event brought together an interdisciplinary group of leading and early-career researchers

Microscopy Meets Medicine: Spirulina-Derived Nanoparticles Take Aim at Cancer

Posted by SANGRAM POLLEY, on 14 April 2025

This article from the International Journal of Nanomedicine presents a promising new biomimetic strategy that makes use of natural resources as an alternative in cancer therapy. The Researchers have created Spirulina-derived Nanoparticles (sNPs) using a solvent-free process and with the aid of centrifugation and sonication technique. The lysosomes sus-pended averaged an approximate size of 126nm,

STED Microscopy User Group, April 10, 12pm EDT

Posted by Ethan A. Perets, on 29 March 2025

The next BioImaging North America and Canada BioImaging STED user group will take place via Zoom on April 10 at 12 pm EST. Mathias Delhaye and Jeffrey LeDue will jointly deliver the presentation, “Expanding Insights: Magnified Analysis of the Proteome Across Imaging Platforms”, followed by Q&A. We hope you will join us! This user group is targeted at

Illuminating Cancer Metabolism: Unveiling Mitochondrial Secrets Through Fluorescence Microscopy

Posted by SANGRAM POLLEY, on 23 March 2025

Understanding cancer metabolism is central to developing effective therapies, and a chief player in this complex scenario is mitochondrial metabolism. The studies of Monika Gooz and Eduardo N. Maldonado have shed light on how fluorescence microscopy is employed to investigate mitochondrial activity in cancer cells, thus posing avenues into the metabolic vulnerabilities that could be

What Happens When Light Meets Cell: Is It Stress, Signal, or Something More?

Posted by Neelabh Datta, on 30 December 2024

In the hub of cellular responses, how does a beam of light trigger a cascade of molecular changes in plant cells? This question solves the mystery of photostimulation-induced stress and signaling, especially at the critical contact points between the endoplasmic reticulum (ER) and chloroplasts. These dynamic cellular sites act as points for communication, resource exchange,

The Crick BioImage Analysis Symposium (2024): conference overview

Posted by zeinab rekad, on 18 December 2024

Have you missed this year’s Crick BioImage Analysis Symposium (CBIAS2024), or you want to know how this conference went to apply for next year’s edition? Here is our recap of this conference featuring impressions from 3 microscopists coming from different research backgrounds: Zeinab Rekad, postdoctoral Research Associate, biologist, super-user and here for the 3rd time

Image Analysis course with Fiji/ImageJ

Posted by Lior Pytowski, on 11 December 2024

Online course introducing you to the basics of image analysis, including automatic segmentation, colocalisation, denoising, 3D, etc.

SAM for Bioimage Analysis: A Comprehensive Guide

Posted by Ranit Karmakar, on 10 December 2024

Image segmentation has always been a cornerstone of image analysis, and in bioimage analysis, its significance cannot be overstated. Precise segmentation of regions of interest is crucial for downstream analysis, yet the inherent complexity of biological data makes this task particularly challenging. While numerous segmentation methods exist, the field has long sought a generalist model

STED User Group (BINA/Canada BioImaging), December 12, 12pm EST

Posted by Ethan A. Perets, on 2 December 2024

The next installment of the BioImaging North America and Canada BioImaging STED user group will take place via Zoom on December 12 at 12 pm EST. Pina Colarusso will deliver the presentation, “Implementing Super Resolution in Core Facilities: Challenges and Opportunities”, followed by group discussion of this important topic. This user group is targeted at STED users of

Can RNA Be a Master Architect?

Posted by Neelabh Datta, on 29 October 2024

How often do we think of RNA as a mere messenger, shuttling genetic instructions between DNA and proteins, rather than the master architect in the construction of cellular structures? While most are familiar with RNA’s role in transcription and translation, the idea that RNA molecules, particularly long ones, could be responsible for organizing intricate, membrane-less

Get involved

Create an account or log in to post your story on FocalPlane.

Featured categories

Microscopy-related articles from our journals

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples Development 2024 151: dev202307
filoVision – using deep learning and tip markers to automate filopodia analysis J Cell Sci 2024 137: jcs261274
C omputational tools for quantifying actin filament numbers, lengths, and bundling Biology Open 2024 13: bio.060267

Microscopy-related preprint highlights

© 2025. The Company of Biologists Ltd | Registered Charity 277992
Registered in England and Wales | Company Limited by Guarantee No 514735
Registered office: Bidder Building, Station Road, Histon, Cambridge CB24 9LF, UK