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A journey of a novice in immunofluorescence assay

Posted by Seth Domfeh, on 15 November 2024

I am Seth Domfeh, a lecturer and an early-career researcher from the Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology, Ghana. I am delighted to share my experience before and during my research visit to the Africa Microscopy Initiative (AMI) Imaging Centre, Institute of Infectious Disease and Molecular Medicine, University of

International Microscopy Facility Survey

Posted by Paul McMillan, on 9 November 2024

Some of you may have seen this already (thanks if you have already filled this in). I have been running an International Microscopy Facility Survey over the last few months. It is based on the excellent BioImaging UK survey that was published a few years ago, but with an extended focus to include Optical Microscopy,

Can RNA Be a Master Architect?

Posted by Neelabh Datta, on 29 October 2024

How often do we think of RNA as a mere messenger, shuttling genetic instructions between DNA and proteins, rather than the master architect in the construction of cellular structures? While most are familiar with RNA’s role in transcription and translation, the idea that RNA molecules, particularly long ones, could be responsible for organizing intricate, membrane-less

When Microtubules Lose Their Grip: The Curious Case of CKAP5 and Chromosomal Chaos

Posted by Neelabh Datta, on 28 October 2024

Have you ever wondered what happens when cells lose control over their microtubule machinery during mitosis? This cellular machinery, when functioning properly, ensures that chromosomes are correctly segregated, preventing aneuploidy and mitotic catastrophe. However, when a protein called CKAP5, which plays a major role in maintaining the stability of microtubule attachments to kinetochores, is knocked

STED User Group (BINA/Canada BioImaging), October 10, 12pm EST

Posted by Ethan A. Perets, on 3 October 2024

The next installment of the BioImaging North America and Canada BioImaging STED user group will take place via Zoom on October 10 at 12 pm EST. Andréanne Deschênes (Université Laval) will deliver a presentation, “Multicolor STED Nanoscopy”, followed by group discussion on topics of community interest. This user group is targeted at users of all experience levels, and

When the collaboration makes it out of the joint lab meeting

Posted by Elizabeth-Ann Legere, on 3 October 2024

I am incredibly grateful to The Company of Biologists (Journal of Cell Science) for funding my three-week research collaboration with the lab of Dr. Gabriel Galea at University College London (UCL). My research in Dr. Aimee Ryan’s lab uses chick embryos to examine cell morphogenetic changes and protein localization patterns during neural tube development, the

Structural Repetition Detector (SReD): quantitative mapping of molecular complexes through microscopy

Posted by Afonso Mendes, on 23 September 2024

Unbiased, multi-dimensional, multi-scale and GPU-accelerated analysis of structural patterns across all microscopy modalities From biomolecules to larger assemblies and cellular architectures, molecular structures govern biological processes. Identifying these repetitive patterns is essential to understand their functions and the underlying biological mechanisms. While microscopy offers molecular-level detail, manually detecting structural motifs is labor-intensive, susceptible to bias,

Image Analysis course with Fiji/ImageJ

Posted by Lior Pytowski, on 18 September 2024

Online course introducing you to the basics of image analysis, including automatic segmentation, colocalisation, denoising, 3D, etc.

From Microscope to Macro-Scope: Same Sobek, New Glyphs

Posted by Daniel Doucet, on 5 September 2024

Thousands of years ago, the Ancient Egyptians depicted their numerous gods on hieroglyphics. One of which is an amalgamation of crocodile and man – Sobek, the god of the Nile River. These sacred carvings (from the classical Greek “heiros”, sacred; “glyphikos”, carving) have to be deciphered carefully by historians who are far removed from the

BioImage.IO Chatbot: Ready to use and discover!

Posted by Caterina Fuster-Barceló, on 21 August 2024

We are delighted to announce the publication of the BioImage.IO Chatbot in Nature Methods this August and its immediate availability for the bioimaging community. This milestone signifies academic recognition and marks the chatbot’s readiness for everyday use in streamlining complex bioimage analysis tasks. Broadening Access to Advanced Bioimage Analysis The BioImage.IO Chatbot, equipped with state-of-the-art

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Microscopy-related articles from our journals

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples Development 2024 151: dev202307
filoVision – using deep learning and tip markers to automate filopodia analysis J Cell Sci 2024 137: jcs261274
C omputational tools for quantifying actin filament numbers, lengths, and bundling Biology Open 2024 13: bio.060267

Microscopy-related preprint highlights

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