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Featured image with Mathieu Preußner

Posted by , on 12 September 2025

Our featured image, acquired by Mathieu Preußner, is a lateral view of the overlying gill arches in 1-month-old Danio rerio expressing endothelial kdrl:mCherry. Clarity-based tissue clearing of the sample enabled comprehensive image acquisition using a Nikon Ti spinning disk system. In ImageJ, the hyperstack was modified using a temporally colour-coded lookup table.
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Featured image with David Grainger

Posted by , on 29 August 2025

Our featured image, acquired by David Grainger, is a colour-coded depth projection of the blood endothelial cells of the E14.5 mouse embryonic thymus and surrounding structures. A 200 μm-thick vibratome section was immunostained for endomucin and imaged on a Zeiss LSM980 confocal microscope and depth-encoded using a rainbow LUT before performing a maximum intensity projection. 
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Featured image with Ludovica Altieri

Posted by , on 15 August 2025

Our featured image, acquired by Ludovica Altieri, shows murine primary cortical neurons developing interconnections. The cells are stained for neuronal tubulin (TUJI antibody, cyan) and DNA (DAPI, blue). Cultures were prepared by dissecting cortices from mouse embryos (E18), then mechanically dissociating single cells for plating. Explanted primary neurons placed in culture regress several stages back,
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Featured image with Krystyna Gieniec

Posted by , on 1 August 2025

Our featured image, 'Unexpected guests' acquired by Krystyna Gieniec, is a 2D culture of mouse mammary fibroblasts stained for Acta2 (magenta) and Vimentin (gold), with some contaminating epithelial cells stained for pan-Cytokeratin (cyan). The image was acquired using a Leica Stellaris 8 confocal microscope.
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Featured image with Maik Bischoff

Posted by , on 18 July 2025

Our featured image, acquired by Maik Bischoff, captures a portion of the testis from the fruit fly Drosophila hydei. Like all insect testes, it is enveloped by a muscle layer. F-actin was stained using phalloidin, making the muscle fibers visible, while DAPI staining revealed the multiple nuclei within each syncytial myotube. An antibody against Drosophila
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Featured image with Lea Berg

Posted by , on 4 July 2025

Our featured image, acquired by Lea Berg and Michael Rassig, shows mature epidermal cell types in a grass leaf of the emerging developmental model system Brachypodium distachyon. Cell outlines are blue, which is plant cell wall UV-autofluorescence. In yellow is stained lignin, a secondary cell wall modification that can be found in the hair cells (shark-tooth-shaped)
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Featured image with Seth Agyei Domfeh

Posted by , on 20 June 2025

Our featured image, acquired by Seth Agyei Domfeh, shows the nuclear localisation of interferon regulatory factor 9 (IRF9) in human hepatoma (HepG2) cells stimulated with interferon α (IFN-α). HepG2 cells were cultured on a poly-D-lysine-coated coverslip for 24 hours and stimulated with 1000 IU/ml IFN-α. At 24 hours post-stimulation, the cells were fixed using 4%
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Featured image with Rosa L. Salgado García

Posted by , on 6 June 2025

Our featured image, acquired by Rosa L. Salgado García, shows a histological section of female (above) and male (below) gonads at an advanced maturation stage of the simultaneous hermaphroditic scallop Nodipecten subnodosus. The image of the gonadic tissue was obtained using a microscope (Leica DM4B) connected to a digital camera (Leica, DMC2900) using LAS V
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Featured image with Andrew Octavian Sasmita

Posted by , on 23 May 2025

Our featured image, acquired by Andrew Octavian Sasmita, depicts a single brain hemisphere of the 5xFAD mouse model of Alzheimer's disease (AD) at different spatial scales.
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Featured image with Rohit Nautiyal

Posted by , on 9 May 2025

Our featured image, acquired by Rohit Nautiyal, shows a monolayer of brain endothelial cells seeded on a glass substrate coated with fibronectin. The cells were fixed and stained for ZO-1 (LUT- Red Hot) to visualize the tight junctions and actin (LUT-blue). The image was captured with a spinning disk confocal microscope and post-processed with Fiji
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