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Featured image with Seth Agyei Domfeh

Posted by , on 20 June 2025

Our featured image, acquired by Seth Agyei Domfeh, shows the nuclear localisation of interferon regulatory factor 9 (IRF9) in human hepatoma (HepG2) cells stimulated with interferon α (IFN-α). HepG2 cells were cultured on a poly-D-lysine-coated coverslip for 24 hours and stimulated with 1000 IU/ml IFN-α. At 24 hours post-stimulation, the cells were fixed using 4%
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Featured image with Rohit Nautiyal

Posted by , on 9 May 2025

Our featured image, acquired by Rohit Nautiyal, shows a monolayer of brain endothelial cells seeded on a glass substrate coated with fibronectin. The cells were fixed and stained for ZO-1 (LUT- Red Hot) to visualize the tight junctions and actin (LUT-blue). The image was captured with a spinning disk confocal microscope and post-processed with Fiji
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A journey of a novice in immunofluorescence assay

Posted by , on 15 November 2024

I am Seth Domfeh, a lecturer and an early-career researcher from the Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology, Ghana. I am delighted to share my experience before and during my research visit to the Africa Microscopy Initiative (AMI) Imaging Centre, Institute of Infectious Disease and Molecular Medicine, University of
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Featured image from Lama Khalaily

Posted by , on 27 September 2024

Our featured image, acquired by Lama Khalaily, captures the intricate structure of a mouse cochlea’s hearing organ, highlighting two essential cell types involved in hair cell regeneration. The image reveals four organized rows of sensory hair cells (red), responsible for hearing, intertwined with non-sensory supporting cells (green). These supporting cells play diverse roles in the
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Featured image with Joe McKellar

Posted by , on 8 December 2023

Our featured image shows a culture of boa constrictor kidney cells that have been transfected with a fusogenic viral protein. This leads to the formation of giant multi-nucleated cells. The cells were transfected with the fusogenic viral protein (shown in gold), left several days for efficient protein expression and for cell fusion to occur, plated
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Featured image with Nick Gatford

Posted by , on 16 November 2023

Our featured image shows a single human dopaminergic neuron generated from a human stem cell, acquired via super-resolution Airyscan confocal microscopy at the University of Oxford Micron facility by Nick Gatford. We caught up with Nick to find out about his research and what he is excited about in microscopy.
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Featured image with Oona Paavolainen

Posted by , on 15 November 2023

Our featured image, acquired by Oona Paavolainen, shows a primary mammary gland organoid, in a collagen-I matrix, formed from a single primary epithelial cell isolated from material obtained from a breast reduction surgery. The image was taken with a spinning disk confocal microscope (3i CSU-W1 Spinning disk) using a 20x Zeiss Plan-Apochromat (NA=0.8) objective. The
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Featured image with Ioakeim (Makis) Ampartzidis

Posted by , on 27 October 2023

Our featured image, ‘Dandelion in spring’ from Ioakeim (Makis) Ampartzidis, shows neuroepithelial-like cells cultured on glass beads. The cell nuclei are coloured in magenta, and the cytoskeleton is stained in black, labelling F-actin. The actively proliferating cells are highlighted with Ki-67 antigen in green. We caught up with Makis to find out more about his
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Featured image with Martín Estermann

Posted by , on 15 September 2023

Our featured image, acquired by Martín Estermann, is a 3D reconstruction of C. elegans transgenic embryos. Embryos were imaged live using a Zeiss Celldiscoverer 7 microscope. The 3D reconstruction was performed using Fiji. Histones in are shown in green and the cell membrane in magenta. We caught up with Martín to find out about his
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20 years of the York confocal course

Posted by , on 11 September 2023

The confocal course at the University of York has been running for 20 years, and I caught up with newly elected RMS President Peter O’Toole at #mmc2023 to discover the history of the course and to find out why it is so successful. With many alumni from the course at the meeting, including at the
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