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JCS snapshot - Dissecting assembly mechanisms of the novel ECM protein SNED1

Posted by FocalPlane, on 26 October 2026

In our latest JCS snapshot we hear from Alexandra Naba who, in two companion papers together with Leanna Leverton, Dharma Pally and team, characterised the understudied ECM protein SNED1 and dissected its role in ECM construction and remodelling. In this video, Alexandra takes us through the key findings from their research.

Workshop report: UC Berkeley’s Advanced Imaging Methods Workshop

Posted by Ben Cox, on 29 May 2025

I attended UC Berkeley’s Advanced Imaging Methods Workshop with goals of becoming more familiar with a) high resolution imaging methods and hardware I did not have access to at my home institution and b) image processing and analysis algorithms, especially those based on machine learning/AI. The workshop provided ample opportunity to fulfill both of these

Interviews and researchers' testimonies from Biologists @ 100

Posted by Margarida Araujo, on 8 May 2025

During the Biologists @ 100 conference, we conducted and recorded interviews with a few researchers to get to know their work better, collecting their testimonies and feedback about the conference. At the end of the interview, researchers were asked to get their picture taken with a ‘polaroid frame’ and write a few keywords about their

Featured image with Omkar Joshi

Posted by FocalPlane, on 14 March 2025

Our featured image, acquired by Omkar Joshi, showcases a U2OS cell immunostained for paxillin (green), TOMM20 (mitochondria, white), and F-actin (labelled using SiR-Actin, magenta), with DAPI (yellow) marking the nucleus.

Kidney elastic fiber network changes in Marfan's Syndrome

Posted by Mario Elias Ortega Sandoval, on 19 July 2024

by de Souza RB*, Meek KM#, Lewis PN#, Pereira LV*. *Department of Genetics and Evolutionary Biology, University of São Paulo, Brazil #StructuralbBiophysics Research Group, School of Optometry and Vision Sciences of the United Kingdom, Cardiff University, UK Challenge Marfan’s syndrome (MFS) is an autosomal dominant disorder that affects the connective tissue, resulting from a mutation

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Microscopy-related articles from our journals

Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface J Cell Sci 2025 138: jcs264154
The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential Development 2025 152: dev204661
The short isoform of Tango1 is dispensable for zebrafish survival but is required for skeletal patterning and integrity Biology Open 2025 14: bio062117

Microscopy-related preprint highlights

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