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Displaying posts with the tag: is_archive

Featured image with the Hughes lab

Posted by , on 20 December 2024

Our featured image, acquired by Sanja Sviben, is an immuno-scanning electron micrograph of a primary cilium, taken from an intact human pancreatic islet. The cilium is a microtubule-based structure and is seen here labeled with colloidal gold for acetylated alpha tubulin.

Featured image with Jiwon Lee

Posted by , on 6 December 2024

Our featured image, acquired by Jiwon Lee, is a 3D rendering model of Plasmodium falciparum showing the complex organisation of cellular organelles within the malaria parasite. Using a focused ion beam scanning electron microscope (FIB-SEM), a series of high resolution 2D images were acquired. The image stack was aligned and each organelle was segmented in

Featured image with Md Hashim Reza

Posted by , on 22 November 2024

Our featured image, prepared by Md Hashim Reza, is an Andy Warhol-inspired illustration of a Candida albicans cell, post-expansion and labelled with BodipyTR, highlighting features of internal membrane organisation.

Featured image with Jyoti Maddhesiya

Posted by , on 8 November 2024

Our featured image, acquired by Jyoti Maddhesiya, is a laser scanning confocal image of H9c2 cardiomyoblast cells. The green shows BMP7 in the cytoplasm, the blue highlights the nuclei and the cytoskeleton protein F-actin is labelled in red. The cells were transfected with a BMP7 construct and fixed and labelled 48 hours post transfection. The

Featured image from Lama Khalaily

Posted by , on 27 September 2024

Our featured image, acquired by Lama Khalaily, captures the intricate structure of a mouse cochlea’s hearing organ, highlighting two essential cell types involved in hair cell regeneration. The image reveals four organized rows of sensory hair cells (red), responsible for hearing, intertwined with non-sensory supporting cells (green). These supporting cells play diverse roles in the

Featured image with Ciarán Butler Hallissey

Posted by , on 13 September 2024

Our featured image, acquired by Ciarán Butler Hallissey, is a maximum-intensity projection of rat hippocampal neurons processed with ultrastructure expansion microscopy (U-ExM) and captured with a spinning disk confocal microscope. Find out more about the image and Ciarán’s research below. More about the image: Expansion microscopy physically increases the size of your sample to improve

Featured image with Shivangi Verma

Posted by , on 30 August 2024

Our featured image, acquired by Shivangi Verma, gives us a peek into the brain of a zebrafish. It depicts neurons in the whole brain of a larva expressing GCaMP6f, a fluorescent reporter of neuronal activity, using a pan-neuronal promoter. A 10-day old transparent homozygous albino larva was embedded in agarose and imaged using ZEISS Lightsheet

Featured image with Marina Schernthanner

Posted by , on 16 August 2024

Our featured image, acquired by Marina Schernthanner, shows the hair follicles of a young (postnatal day 9) C57B6 mouse’s back skin. By using ethanol-based tissue clearing, Mariana stained fixed whole-mount tissue samples of the murine skin after removing the surface haircoat and subcutaneous fat layer. LYVE-1 (orange) marks the lymphatic vasculature, Keratin-14 (red) highlights the

Featured image with Upasana Gupta

Posted by , on 2 August 2024

Our featured image, acquired by Upasana Gupta, represents the cellular architecture of zebrafish (larva) eye. The tissue was prepared by paraformaldehyde fixation of a 4-day post fertilisation larva, followed by staining with Hoechst nuclear stain. The sample was imaged and processed using Leica SP8 confocal microscope and Leica software at the Bio-imaging facility at the

Featured image with Jovan Brockett

Posted by , on 19 July 2024

Our featured image, acquired by Jovan Brockett, shows a Drosophila melanogaster embryo undergoing syncytial nuclear divisions during early embryonic development. It was prepared using PFA fixation and hand dissected to remove the outer vitelline membrane. The image was captured using a Nikon Ti-E system fitted with a Yokagawa CSU-X1 spinning disk head, Hamamatsu Orca Flash