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Featured image with Seth Agyei Domfeh

Posted by , on 20 June 2025

Our featured image, acquired by Seth Agyei Domfeh, shows the nuclear localisation of interferon regulatory factor 9 (IRF9) in human hepatoma (HepG2) cells stimulated with interferon α (IFN-α). HepG2 cells were cultured on a poly-D-lysine-coated coverslip for 24 hours and stimulated with 1000 IU/ml IFN-α. At 24 hours post-stimulation, the cells were fixed using 4%
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Featured image with Rosa L. Salgado García

Posted by , on 6 June 2025

Our featured image, acquired by Rosa L. Salgado García, shows a histological section of female (above) and male (below) gonads at an advanced maturation stage of the simultaneous hermaphroditic scallop Nodipecten subnodosus. The image of the gonadic tissue was obtained using a microscope (Leica DM4B) connected to a digital camera (Leica, DMC2900) using LAS V
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Featured image with Andrew Octavian Sasmita

Posted by , on 23 May 2025

Our featured image, acquired by Andrew Octavian Sasmita, depicts a single brain hemisphere of the 5xFAD mouse model of Alzheimer's disease (AD) at different spatial scales.
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Featured image with Rohit Nautiyal

Posted by , on 9 May 2025

Our featured image, acquired by Rohit Nautiyal, shows a monolayer of brain endothelial cells seeded on a glass substrate coated with fibronectin. The cells were fixed and stained for ZO-1 (LUT- Red Hot) to visualize the tight junctions and actin (LUT-blue). The image was captured with a spinning disk confocal microscope and post-processed with Fiji
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Featured image with Saurabh Chand Sagar

Posted by , on 25 April 2025

Our featured image, acquired by Saurabh Chand Sagar, presents a laser scanning confocal projection of the Malpighian tubules (MTs) from third instar wandering-stage (118 ± 2 hours post-eclosion) wild-type Drosophila melanogaster larvae. In the image, red denotes F-actin protein, green highlights Discs Large, a protein involved in maintenance of apicobasal polarity, and blue marks the
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Featured image with Subhajit Karmakar

Posted by , on 11 April 2025

Our featured image, acquired by Subhajit Karmakar, depicts a dividing MDA-MB-231 cancer cell that has been stained to visualise the localisation of two key proteins: CK2, a highly oncogenic kinase, and an E3 ligase, a tumour suppressor.
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Featured image with Omkar Joshi

Posted by , on 14 March 2025

Our featured image, acquired by Omkar Joshi, showcases a U2OS cell immunostained for paxillin (green), TOMM20 (mitochondria, white), and F-actin (labelled using SiR-Actin, magenta), with DAPI (yellow) marking the nucleus.
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Featured image with Anthony Dornan and Fara van der Schans

Posted by , on 28 February 2025

Our featured image, acquired by Anthony Dornan and Fara van der Schans, showcases the perinuclear distribution of mitochondria in the highly respiratory human pancreatic ductal adenocarcinoma (PDAC) tumour cells (Panc-1) stained with the mitochondrial stain TMRE (thermal LUT), the mitochondria are associated with the nuclei, stained with DAPI (cyan). The live cell image is a maximum intensity Z-projection generated
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Featured image with Amy Engevik

Posted by , on 14 February 2025

Our featured image, acquired by Amy Engevik, shows a differentiated intestinal organoid from a germline Myosin 5b knockout mouse.
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Featured image with the Hughes lab

Posted by , on 20 December 2024

Our featured image, acquired by Sanja Sviben, is an immuno-scanning electron micrograph of a primary cilium, taken from an intact human pancreatic islet. The cilium is a microtubule-based structure and is seen here labeled with colloidal gold for acetylated alpha tubulin.
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