featured image - FocalPlane

Displaying posts with the tag: is_archive
Clear filters

Featured image with Jyoti Maddhesiya

Posted by FocalPlane, on 8 November 2024

Our featured image, acquired by Jyoti Maddhesiya, is a laser scanning confocal image of H9c2 cardiomyoblast cells. The green shows BMP7 in the cytoplasm, the blue highlights the nuclei and the cytoskeleton protein F-actin is labelled in red. The cells were transfected with a BMP7 construct and fixed and labelled 48 hours post transfection. The

Featured image from Lama Khalaily

Posted by FocalPlane, on 27 September 2024

Our featured image, acquired by Lama Khalaily, captures the intricate structure of a mouse cochlea’s hearing organ, highlighting two essential cell types involved in hair cell regeneration. The image reveals four organized rows of sensory hair cells (red), responsible for hearing, intertwined with non-sensory supporting cells (green). These supporting cells play diverse roles in the

Featured image with Ciarán Butler Hallissey

Posted by FocalPlane, on 13 September 2024

Our featured image, acquired by Ciarán Butler Hallissey, is a maximum-intensity projection of rat hippocampal neurons processed with ultrastructure expansion microscopy (U-ExM) and captured with a spinning disk confocal microscope. Find out more about the image and Ciarán’s research below. More about the image: Expansion microscopy physically increases the size of your sample to improve

Featured image with Shivangi Verma

Posted by FocalPlane, on 30 August 2024

Our featured image, acquired by Shivangi Verma, gives us a peek into the brain of a zebrafish. It depicts neurons in the whole brain of a larva expressing GCaMP6f, a fluorescent reporter of neuronal activity, using a pan-neuronal promoter. A 10-day old transparent homozygous albino larva was embedded in agarose and imaged using ZEISS Lightsheet

Featured image with Marina Schernthanner

Posted by FocalPlane, on 16 August 2024

Our featured image, acquired by Marina Schernthanner, shows the hair follicles of a young (postnatal day 9) C57B6 mouse’s back skin. By using ethanol-based tissue clearing, Mariana stained fixed whole-mount tissue samples of the murine skin after removing the surface haircoat and subcutaneous fat layer. LYVE-1 (orange) marks the lymphatic vasculature, Keratin-14 (red) highlights the

Featured image with Upasana Gupta

Posted by FocalPlane, on 2 August 2024

Our featured image, acquired by Upasana Gupta, represents the cellular architecture of zebrafish (larva) eye. The tissue was prepared by paraformaldehyde fixation of a 4-day post fertilisation larva, followed by staining with Hoechst nuclear stain. The sample was imaged and processed using Leica SP8 confocal microscope and Leica software at the Bio-imaging facility at the

Featured image with Jovan Brockett

Posted by FocalPlane, on 19 July 2024

Our featured image, acquired by Jovan Brockett, shows a Drosophila melanogaster embryo undergoing syncytial nuclear divisions during early embryonic development. It was prepared using PFA fixation and hand dissected to remove the outer vitelline membrane. The image was captured using a Nikon Ti-E system fitted with a Yokagawa CSU-X1 spinning disk head, Hamamatsu Orca Flash

Featured image with Hoang Anh Le

Posted by FocalPlane, on 5 July 2024

Our featured image, acquired by Hoang Anh Le, shows an Ewing’s sarcoma cancer cell plated on a fibronectin-coated surface. The cell was fixed with 4% formaldehyde and stained using phalloidin (white) and DAPI (in pink). The sample was imaged using a confocal Zeiss 880 microscope with Airyscan.

Featured image with Theresa Wiesner

Posted by FocalPlane, on 21 June 2024

Our featured image, acquired by Theresa Wiesner, shows a neuron in dissociated hippocampal culture and was imaged using highly inclined thin illumination microscopy (HiLO). The neuron is transfected with a neurotransmitter (glutamate) sensor and shown in orange. The image was acquired using Nikon Elements software / microscope and post-processing was done using FIJI (ImageJ). Find

Featured image with Thibault Dhellemmes and Jérémie Teillon

Posted by FocalPlane, on 1 March 2024

Our featured image shows the full morphology of Relaxin-3 neurons in an entire adult mouse brain. To observe the full depth of this brain, it was made transparent by applying an optical clearing technique called Adipoclear. The sample was observed on an Ultramicroscope II light sheet microscope and is a maximum intensity projection over the

Get involved

Create an account or log in to post your story on FocalPlane.

Featured categories

Microscopy-related articles from our journals

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples Development 2024 151: dev202307
filoVision – using deep learning and tip markers to automate filopodia analysis J Cell Sci 2024 137: jcs261274
C omputational tools for quantifying actin filament numbers, lengths, and bundling Biology Open 2024 13: bio.060267

Microscopy-related preprint highlights

© 2024. The Company of Biologists Ltd | Registered Charity 277992
Registered in England and Wales | Company Limited by Guarantee No 514735
Registered office: Bidder Building, Station Road, Histon, Cambridge CB24 9LF, UK

Displaying posts with the tag: is_archive Clear filters

Get involved

Featured categories

Microscopy-related articles from our journals

Microscopy-related preprint highlights

Displaying posts with the tag: is_archive
Clear filters