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Featured image with Marina Schernthanner

Posted by , on 16 August 2024

Our featured image, acquired by Marina Schernthanner, shows the hair follicles of a young (postnatal day 9) C57B6 mouse’s back skin. By using ethanol-based tissue clearing, Mariana stained fixed whole-mount tissue samples of the murine skin after removing the surface haircoat and subcutaneous fat layer. LYVE-1 (orange) marks the lymphatic vasculature, Keratin-14 (red) highlights the
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Featured image with Upasana Gupta

Posted by , on 2 August 2024

Our featured image, acquired by Upasana Gupta, represents the cellular architecture of zebrafish (larva) eye. The tissue was prepared by paraformaldehyde fixation of a 4-day post fertilisation larva, followed by staining with Hoechst nuclear stain. The sample was imaged and processed using Leica SP8 confocal microscope and Leica software at the Bio-imaging facility at the
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Featured image with Jovan Brockett

Posted by , on 19 July 2024

Our featured image, acquired by Jovan Brockett, shows a Drosophila melanogaster embryo undergoing syncytial nuclear divisions during early embryonic development. It was prepared using PFA fixation and hand dissected to remove the outer vitelline membrane. The image was captured using a Nikon Ti-E system fitted with a Yokagawa CSU-X1 spinning disk head, Hamamatsu Orca Flash
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Featured image with Hoang Anh Le

Posted by , on 5 July 2024

Our featured image, acquired by Hoang Anh Le, shows an Ewing’s sarcoma cancer cell plated on a fibronectin-coated surface. The cell was fixed with 4% formaldehyde and stained using phalloidin (white) and DAPI (in pink). The sample was imaged using a confocal Zeiss 880 microscope with Airyscan.
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Featured image with Theresa Wiesner

Posted by , on 21 June 2024

Our featured image, acquired by Theresa Wiesner, shows a neuron in dissociated hippocampal culture and was imaged using highly inclined thin illumination microscopy (HiLO). The neuron is transfected with a neurotransmitter (glutamate) sensor and shown in orange. The image was acquired using Nikon Elements software / microscope and post-processing was done using FIJI (ImageJ). Find
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Featured image with Thibault Dhellemmes and Jérémie Teillon

Posted by , on 1 March 2024

Our featured image shows the full morphology of Relaxin-3 neurons in an entire adult mouse brain. To observe the full depth of this brain, it was made transparent by applying an optical clearing technique called Adipoclear. The sample was observed on an Ultramicroscope II light sheet microscope and is a maximum intensity projection over the
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Featured image with Rossana Melo

Posted by , on 16 February 2024

Our featured image, acquired by Rossana Melo, shows a human eosinophil isolated from the peripheral blood using a negative immunomagnetic selection method and prepared for transmission electron microscopy (TEM). The image was acquired with a Tecnai G2 Spirit Bio Twin ThermoFisher Scientific (former FEI) electron microscope.
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Featured image with Virginia Barrera

Posted by , on 2 February 2024

Our featured image was acquired by Virginia Barrera and was the winning image from the Institute of Molecular and Cellular Biology of Rosario (IBR-CONICET) annual retreat. It depicts a transversal cut of a soybean, with Calcofluor White staining cellulose and Basic Fuchsine labelling lignin.
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Featured images in 2023

Posted by , on 5 January 2024

In 2023, we started a featured image series and we have been delighted to highlight the microscopists that acquired these beautiful images! You can check out the full series here and in the gallery below. We are continuing the series in 2024 and would love to have nominations, including self-nominations. Send us an email at
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Featured image with Joe McKellar

Posted by , on 8 December 2023

Our featured image shows a culture of boa constrictor kidney cells that have been transfected with a fusogenic viral protein. This leads to the formation of giant multi-nucleated cells. The cells were transfected with the fusogenic viral protein (shown in gold), left several days for efficient protein expression and for cell fusion to occur, plated
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