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Featured image with Hoang Anh Le

Posted by , on 5 July 2024

Our featured image, acquired by Hoang Anh Le, shows an Ewing’s sarcoma cancer cell plated on a fibronectin-coated surface. The cell was fixed with 4% formaldehyde and stained using phalloidin (white) and DAPI (in pink). The sample was imaged using a confocal Zeiss 880 microscope with Airyscan.
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Featured image with Theresa Wiesner

Posted by , on 21 June 2024

Our featured image, acquired by Theresa Wiesner, shows a neuron in dissociated hippocampal culture and was imaged using highly inclined thin illumination microscopy (HiLO). The neuron is transfected with a neurotransmitter (glutamate) sensor and shown in orange. The image was acquired using Nikon Elements software / microscope and post-processing was done using FIJI (ImageJ). Find
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Featured image with Thibault Dhellemmes and Jérémie Teillon

Posted by , on 1 March 2024

Our featured image shows the full morphology of Relaxin-3 neurons in an entire adult mouse brain. To observe the full depth of this brain, it was made transparent by applying an optical clearing technique called Adipoclear. The sample was observed on an Ultramicroscope II light sheet microscope and is a maximum intensity projection over the
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Featured image with Rossana Melo

Posted by , on 16 February 2024

Our featured image, acquired by Rossana Melo, shows a human eosinophil isolated from the peripheral blood using a negative immunomagnetic selection method and prepared for transmission electron microscopy (TEM). The image was acquired with a Tecnai G2 Spirit Bio Twin ThermoFisher Scientific (former FEI) electron microscope.
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Featured image with Virginia Barrera

Posted by , on 2 February 2024

Our featured image was acquired by Virginia Barrera and was the winning image from the Institute of Molecular and Cellular Biology of Rosario (IBR-CONICET) annual retreat. It depicts a transversal cut of a soybean, with Calcofluor White staining cellulose and Basic Fuchsine labelling lignin.
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Featured images in 2023

Posted by , on 5 January 2024

In 2023, we started a featured image series and we have been delighted to highlight the microscopists that acquired these beautiful images! You can check out the full series here and in the gallery below. We are continuing the series in 2024 and would love to have nominations, including self-nominations. Send us an email at
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Featured image with Joe McKellar

Posted by , on 8 December 2023

Our featured image shows a culture of boa constrictor kidney cells that have been transfected with a fusogenic viral protein. This leads to the formation of giant multi-nucleated cells. The cells were transfected with the fusogenic viral protein (shown in gold), left several days for efficient protein expression and for cell fusion to occur, plated
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Featured image with Nick Gatford

Posted by , on 16 November 2023

Our featured image shows a single human dopaminergic neuron generated from a human stem cell, acquired via super-resolution Airyscan confocal microscopy at the University of Oxford Micron facility by Nick Gatford. We caught up with Nick to find out about his research and what he is excited about in microscopy.
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Featured image with Oona Paavolainen

Posted by , on 15 November 2023

Our featured image, acquired by Oona Paavolainen, shows a primary mammary gland organoid, in a collagen-I matrix, formed from a single primary epithelial cell isolated from material obtained from a breast reduction surgery. The image was taken with a spinning disk confocal microscope (3i CSU-W1 Spinning disk) using a 20x Zeiss Plan-Apochromat (NA=0.8) objective. The
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Featured image with Till Stephan

Posted by , on 14 November 2023

Our featured image, acquired by Till Stephan, shows a live-cell stimulated emission depletion (STED) microscopy recording of a HeLa cell in which mitochondria (orange-magenta) and microtubules (cyan) are labelled. The super-resolution image reveals the densely stacked mitochondrial cristae, coordinated invaginations of the mitochondrial inner membrane.
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