JCS snapshots - FocalPlane

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JCS snapshot - Golgi disintegration and functional disruption during paraptosis

Posted by FocalPlane, on 19 August 2026

In our latest JCS snapshot we hear from Xiang Cui, who, together with Min Cui and team, uncover a role for Golgi disintegration and functional disruption during paraptosis. In this snapshot, Xiang Cui take us through the key findings from their research.

JCS snapshot - Live imaging of epithelial phagocyte differentiation in the Drosophila ovary reveals transient and novel behaviours

Posted by FocalPlane, on 11 August 2026

In our latest JCS snapshot we hear from Caique Almeida Machado Costa, who, together with Wu-Min Deng and team, used time-lapse imaging to uncover dynamic behaviours during epithelial-to-phagocyte differentiation, including migration, delamination, long-range target capture and cell engulfment. In this snapshot, Cai take us through the key findings from their research.

JCS snapshot: A ULK1–MTFR1L feedback loop links mitochondrial fission, mitophagy and apoptosis

Posted by FocalPlane, on 22 July 2026

In our latest JCS snapshot we hear from Riccardo Babic, Leon Lucya and Christoph Reiter, who, together with Claudine Kraft and team, identified a ULK1–MTFR1L feedback loop that links mitochondrial fission, mitophagy and apoptosis.

JCS snapshot: Redefining colocalization analysis with a novel phasor mixing coefficient

Posted by FocalPlane, on 6 March 2026

In our latest JCS snapshot we hear from Owen Puls, who together with Teng-Leong Chew and team define a new strategy for quantifying biological association that leverages multispectral imaging and phasor analysis, termed the phasor mixing coefficient (PMC). In this snapshot, Owen takes us through the key findings from their research.

JCS snapshot: Suppressing microtubule detyrosination augments AAV2 endosomal escape & gene delivery

Posted by FocalPlane, on 19 February 2026

In our latest JCS snapshot we hear from Shefali Tripathi, who, together with Nitin Mohan, Giridhara Jayandharan and team, found that suppressing microtubule detyrosination augments adeno-associated virus 2 endosomal escape and gene delivery.

JCS snapshot: RNP1A regulates cell shape in Dictyostelium amoebas

Posted by FocalPlane, on 12 February 2026

In our latest JCS snapshot we hear from Mark Jacob, who, together with Yinan Liu, Douglas Robinson and team, found that the RNA-binding protein RNP1A regulates cell shape in Dictyostelium amoebas. In this snapshot, Mark takes us through the key findings from their research.

JCS snapshot: Tracking coordinated cellular dynamics in time-lapse microscopy with ARCOS.px

Posted by FocalPlane, on 29 January 2026

In our latest JCS snapshot we hear from Maciej Dobrzyński, who, together with Benjamin Grädel and colleagues, developed ARCOS.px, a software tool to automatically identify and track coordinated dynamic cellular events in time-lapse microscopy movies.

JCS snapshot: the endoplasmic reticulum protein FAM134B acts as a regulator of mitochondrial morphology

Posted by FocalPlane, on 14 January 2026

In our latest JCS snapshot we hear from Sebabrata Maity, who, together with Oishee Chakrabarti and colleagues, discovered that the endoplasmic reticulum protein FAM134B acts as a regulator of mitochondrial morphology.

JCS snapshot - Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation

Posted by FocalPlane, on 12 January 2026

In our latest JCS snapshot we hear from Anne Müsch, who, together with David Cohen and Francisco Lázaro-Diéguez, discovered that bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation.

New JCS snapshot: The MLL/WDR5 complex promotes midbody recruitment of KIF2C for microtubule depolymerisation and furrow initiation during cytokinesis

Posted by FocalPlane, on 10 December 2025

In our latest JCS snapshot we hear from Avishek Kataria, who, together with Shweta Tyagi and colleagues, discovered that the MLL/WDR5 complex promotes midbody recruitment of KIF2C for microtubule depolymerisation and furrow initiation during cytokinesis. In this snapshot, Avishek takes us through the key findings from their research.

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