Featured image with Beste Senem Değirmenci

Posted by FocalPlane, on 18 August 2023

Our featured image, ‘Bubbles of The Cell’, shows enlarged endosomal vesicles in HeLa S3 cells upon inhibition of PI(3,5)P2 activity. PI(3,5)P2 is a crucial phosphoinositide involved in the regulation of endosomal trafficking. Depletion of PI(3,5)P2 disrupts the transition from early to late endosomes, leading to the enlargement of endosomal vesicles. Imaged with Leica DMI8 SP8