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FocalPlane

Posts from the FocalPlane team

About FocalPlane

Microscopy background: Optical System Development, Image Analysis, Probe Development

Posts by FocalPlane

JCS snapshot - Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation

Posted by , on 12 January 2026

In our latest JCS snapshot we hear from Anne Müsch, who, together with David Cohen and Francisco Lázaro-Diéguez, discovered that bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation.

Microscopy preprints – new tools and techniques in imaging

Posted by , on 9 January 2026

Here is a curated selection of preprints posted recently on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!

Imaging spotlight: Lock-in-SIM

Posted by , on 8 January 2026

In this paper highlight from Wenjie Liu and colleagues, we learn about Lock-in-SIM, a new methodology for structured illumination microscopy.

Featured image with Christina Daly

Posted by , on 6 January 2026

Our featured image, acquired by Christina Daly, is of an E9.5 murine neural tube. The embryo was fixed in 4% Paraformaldehyde, embedded in agarose, and vibratome-sectioned at 100 mm thickness. The sections were stained with for F-actin with phalloidin and imaged on a Nikon A1R confocal.

Microscopy preprints: bioimage analysis

Posted by , on 29 December 2025

Here is a curated selection of preprints published (or updated) recently. In this post we focus specifically on bioimage analysis and data management.

Recent events by FocalPlane

XXXI SIBPA-IVSLA International School of Pure and Applied Biophysics: "Multiphoton and Multiharmonic Microscopy for the Life Sciences: Principles and Applications"

Abstract submission deadline: 1st October 2026

Early registration deadline: 1st August 2026

Location: Palaiseau, FR

Date: 18 January 2027 — 22 January 2027

International conference on Imaging and Characterisation for a Sustainable World ICWORLD 2027

Abstract submission deadline: 31st July 2026

Early registration deadline: 30th September 2026

Location: Oulu, Finland

Date: 13 January 2027 — 15 January 2027

AI and computational biology

Abstract submission deadline: 7th October 2026

Early registration deadline: 28th October 2026

Location: Leuven, Belgium

Date: 9 December 2026 — 10 December 2026