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Featured image with Marina Schernthanner

Posted by FocalPlane, on 16 August 2024

Our featured image, acquired by Marina Schernthanner, shows the hair follicles of a young (postnatal day 9) C57B6 mouse’s back skin. By using ethanol-based tissue clearing, Mariana stained fixed whole-mount tissue samples of the murine skin after removing the surface haircoat and subcutaneous fat layer. LYVE-1 (orange) marks the lymphatic vasculature, Keratin-14 (red) highlights the

New Intern for FocalPlane

Posted by Ryan Harrison, on 14 August 2024

Hi everyone! My name is Ryan Harrison and I’m an intern who will be working on the community sites at The Company of Biologists, including FocalPlane, for the next three months.

Merfish-ing across the Pacific: from New Zealand to California, USA

Posted by Maize Cao, on 12 August 2024

I am an early career postdoc at the University of Auckland (UoA), New Zealand. My research interest is in neurodegeneration and molecular biology, with a focus on RNA biology and omics. My current work is dedicated to people who live with a devasting neurological disorder known as amyotrophic lateral sclerosis (ALS). This disease is usually

Microscopy preprints – new tools and techniques in imaging

Posted by FocalPlane, on 9 August 2024

Here is a curated selection of preprints posted recently on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!

Introducing SciCommConnect three-minute talk winner Oliver Anderson

Posted by Helen Zenner, on 7 August 2024

In June, the Node, preLights and FocalPlane hosted SciCommConnect, a science communication event focussed on learning new scicomm skills and networking with like-minded researchers. As part of the day, we hosted a three-minute research talk competition, and we were treated to 12 fantastic talks on a range of topics. We had two competition winners, Oliver

Featured image with Upasana Gupta

Posted by FocalPlane, on 2 August 2024

Our featured image, acquired by Upasana Gupta, represents the cellular architecture of zebrafish (larva) eye. The tissue was prepared by paraformaldehyde fixation of a 4-day post fertilisation larva, followed by staining with Hoechst nuclear stain. The sample was imaged and processed using Leica SP8 confocal microscope and Leica software at the Bio-imaging facility at the

Journal of Cell Science cover competition

Posted by FocalPlane, on 29 July 2024

We’re looking for a spectacular image for the cover of our special issue on ‘Imaging Cell Architecture and Dynamics’. If you have an image that fits that theme, send it over for your chance to be featured on the cover of JCS and to win £200. The special issue is being coordinated by our Guest

Microscopy preprints – bioimage analysis

Posted by FocalPlane, on 29 July 2024

Here is a curated selection of preprints published recently. In this post, we focus specifically on bioimage analysis and data management.

Kidney elastic fiber network changes in Marfan's Syndrome

Posted by Mario Elias Ortega Sandoval, on 19 July 2024

by de Souza RB*, Meek KM#, Lewis PN#, Pereira LV*. *Department of Genetics and Evolutionary Biology, University of São Paulo, Brazil #StructuralbBiophysics Research Group, School of Optometry and Vision Sciences of the United Kingdom, Cardiff University, UK Challenge Marfan’s syndrome (MFS) is an autosomal dominant disorder that affects the connective tissue, resulting from a mutation

Featured image with Jovan Brockett

Posted by FocalPlane, on 19 July 2024

Our featured image, acquired by Jovan Brockett, shows a Drosophila melanogaster embryo undergoing syncytial nuclear divisions during early embryonic development. It was prepared using PFA fixation and hand dissected to remove the outer vitelline membrane. The image was captured using a Nikon Ti-E system fitted with a Yokagawa CSU-X1 spinning disk head, Hamamatsu Orca Flash

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Microscopy-related articles from our journals

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples Development 2024 151: dev202307
filoVision – using deep learning and tip markers to automate filopodia analysis J Cell Sci 2024 137: jcs261274
C omputational tools for quantifying actin filament numbers, lengths, and bundling Biology Open 2024 13: bio.060267

Microscopy-related preprint highlights

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