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JCS snapshot: RNP1A regulates cell shape in Dictyostelium amoebas

Posted by , on 12 February 2026

In our latest JCS snapshot we hear from Mark Jacob, who, together with Yinan Liu, Douglas Robinson and team, found that the RNA-binding protein RNP1A regulates cell shape in Dictyostelium amoebas. In this snapshot, Mark takes us through the key findings from their research.
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Imaging spotlight - How to divide without a ring: a mechanical ratchet drives unilateral cytokinesis

Posted by , on 10 February 2026

In this paper highlight, Jan Brugués and Alison Kickuth discuss the microscopy and microrheology techniques that they used in their research dissecting the mechanics of cytokinesis.
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Workshop report: EMBO Course on Image Processing in Cryo-EM

Posted by , on 9 February 2026

Freya Cardozo shares her workshop report from the EMBO course on Imaging Processing in Cryo-EM. Freya's attendance was supported with a JCS-FocalPlane Training Grant.
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Imaging spotlight: ShapeSpaceExplorer

Posted by , on 5 February 2026

In this paper highlight, we learn about ShapeSpaceExplorer, a tool for measuring cell shape of migrating cells, developed by Samuel Jefferyes, Anne Straube and colleagues.
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Microscopy preprints – applications in biology

Posted by , on 23 January 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Cytoneme Imaging Tips and Tricks

Posted by , on 19 January 2026

There has been a growing interest in visualizing long and thin membrane extensions. The field of intercellular connections has exploded, with elegant bioimaging studies focusing on structures like cytonemes, tunneling nanotubes (TNTs), intercellular/cytokinetic bridges (IB/CBs), and migrasomes. This enhanced interest in the intercellular communication facilitated by these extensions is largely due to the recent technological
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Imaging spotlight: Initiation of chromosome congression deconstructed by multi-scale live lattice light-sheet and super-resolution microscopy

Posted by , on 16 January 2026

In this highlight, Kruno Vukušić and Iva M. Tolić describe how they use multi-scale live lattice light-sheet and super-resolution microscopy to decipher the earliest steps of chromosome congression.
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JCS snapshot: the endoplasmic reticulum protein FAM134B acts as a regulator of mitochondrial morphology

Posted by , on 14 January 2026

In our latest JCS snapshot we hear from Sebabrata Maity, who, together with Oishee Chakrabarti and colleagues, discovered that the endoplasmic reticulum protein FAM134B acts as a regulator of mitochondrial morphology.
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JCS snapshot - Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation

Posted by , on 12 January 2026

In our latest JCS snapshot we hear from Anne Müsch, who, together with David Cohen and Francisco Lázaro-Diéguez, discovered that bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation.
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Imaging spotlight: Lock-in-SIM

Posted by , on 8 January 2026

In this paper highlight from Wenjie Liu and colleagues, we learn about Lock-in-SIM, a new methodology for structured illumination microscopy.
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