cryo-electron tomography

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FocalPlane features... Marcel Dickmanns and Laura Copeland - recordings

Posted by FocalPlane, on 26 October 2026

In October, we heard from Marcel Dickmanns on ‘Exploring the Molecular Landscape within Plant Cells by Cryo-Electron Tomography’ and Laura Copeland on ‘Multimodal Quantitative Fourier Ptychographic Microscopy and Fluorescence Imaging Reveals Stable Bacterial Colonisation Architecture Under Phosphate Limitation’. You can find the recordings of the talks here.

Register now for FocalPlane features... quantitative plant imaging

Posted by FocalPlane, on 23 September 2026

In this webinar, we'll hear from Marcel Dickmanns on 'Exploring the Molecular Landscape within Plant Cells by Cryo-Electron Tomography' and Laura Copeland on 'Multimodal Quantitative Fourier Ptychographic Microscopy and Fluorescence Imaging Reveals Stable Bacterial Colonisation Architecture Under Phosphate Limitation'.

Microscopy preprints: applications in biology

Posted by FocalPlane, on 29 May 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.

Back to the density: using Surface Morphometrics to measure organelle membrane thickness in cryo-electron tomography

Posted by Michaela Medina, on 18 March 2026

Surface Morphometrics is an open-access software that extracts quantitative information of membrane ultrastructure from high resolution cryo-electron tomography (cryo-ET) data. This tooling allows for the study of organelles in their native environment across large populations in an automated fashion. The Surface Morphometrics pipeline reconstructs three-dimensional triangular surface meshes to model and quantify the cellular membrane

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Microscopy-related articles from our journals

Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface J Cell Sci 2025 138: jcs264154
The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential Development 2025 152: dev204661
The short isoform of Tango1 is dispensable for zebrafish survival but is required for skeletal patterning and integrity Biology Open 2025 14: bio062117

Microscopy-related preprint highlights

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