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Imaging spotlight: Revealing mouse brain ultrastructure using non-destructive X-ray tomography

Posted by FocalPlane, on 13 January 2026

In this paper highlight, Carles Bosch, Ana Diaz, Adrian A. Wanner and Andreas T. Schaefer (on behalf of all authors) describe how they use nondestructive X-ray tomography to map mouse brain tissue ultrastructure .

Imaging spotlight: Lock-in-SIM

Posted by FocalPlane, on 8 January 2026

In this paper highlight from Wenjie Liu and colleagues, we learn about Lock-in-SIM, a new methodology for structured illumination microscopy.

Imaging spotlight: u-Segment3D

Posted by FocalPlane, on 11 December 2025

In this paper highlight, we learn about u-Segment3D, a software framework developed by Felix Zhou and Gaudenz Danuser and colleagues.

Imaging spotlight: Volumetric Imaging via Photochemical Sectioning (VIPS)

Posted by FocalPlane, on 2 December 2025

In this paper highlight, we learn more about VIPS, a method developed by Srigokul Upadhyayula, Ruixuan Gao and colleagues.

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Microscopy-related articles from our journals

Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface J Cell Sci 2025 138: jcs264154
The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential Development 2025 152: dev204661
The short isoform of Tango1 is dispensable for zebrafish survival but is required for skeletal patterning and integrity Biology Open 2025 14: bio062117

Microscopy-related preprint highlights

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