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All things unequal – live microscopy reveals asymmetric RNA localization in the early mammalian embryo

Posted by Jennifer Zenker, on 4 September 2023

Authors: Jennifer Zenker1,*, Julian Heng2 1Australian Regenerative Medicine Institute (ARMI), Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Australia 2Remotely Consulting, Perth, Australia *Corresponding author Non-mammalian systems have been invaluable for us to decipher evolutionarily-conserved processes, orthologous molecules and cellular phenomena underlying early embryo development. One fundamental discovery from the work on non-mammalian

Tracking in napari

Posted by Mara Lampert, on 1 June 2023

In this blog post we are exploring cell tracking in napari. Two important processes in normal tissue development and disease are cell migration and proliferation. To gain a better understanding on these processes, tracking in time-lapse datasets is needed. By measuring track properties, like velocity and the total travelled distance, spatio-temporal relationships can be studied.

Director of Cambridge Advanced Imaging Centre and SBS Microscopy Network at University of Cambridge

Posted by Antonina Kruppa, on 31 May 2023

https://www.jobs.cam.ac.uk/job/40627/ Closing Date: 30 June 2023.

Feature extraction in napari

Posted by Mara Lampert, on 3 May 2023

This blog post revolves around extracting and selecting features from segmented images. We will define the terms feature extraction and selection. Also, we will learn how to categorize features and can look up specific features in a glossary. Furthermore, we will explore how to extract features in napari. Definition of feature extraction During feature extraction,

Annotating 3D images in napari

Posted by Mara Lampert, on 30 March 2023

This blog post revolves around generating ground truth in 3D images for segmentation. Therefore, we will define what ground truth is and how we can generate it using napari in a time-efficient way. We will also learn about difficulties of annotating alone or in groups and address possible solutions for both. Challenges of image segmentation

Rescaling images and pixel (an)isotropy

Posted by Mara Lampert, on 2 March 2023

This blog post shows the importance of rescaling 3D image data and what anisotropy of pixels/voxels has to do with it. We will see which different options exist to rescale an image as well as their advantages and limitations. We will also apply a commonly used segmentation algorithm, Voronoi-Otsu-Labeling, on the original and the rescaled

VollSeg and its extension Napari plugins

Posted by varun kapoor, on 15 January 2023

In this article we present the Napari plugin VollSeg and its ongoing extension plugins that we are creating as a part of the CZI grant awarded successively to the non-profit company KapoorLabs, Paris. VollSeg is a Napari plugin for performing semantic, instance segmentation and denoising using the seed pooling approach that requires StarDist and either

Job Opportunity: Scientific Officer on Smart Microscopy at the Centre for Cellular Imaging of Gothenburg University

Posted by Rafael Camacho, on 9 January 2023

We are looking for a new colleague (Scientific Officer) at the Centre for Cellular Imaging of Gothenburg University (CCI). The CCI, in operation since 2003, is a national research infrastructure and one of the leading academic imaging facilities in Sweden providing expertise and access to advanced microscopy to the research community, both locally and at other Swedish

Crick BioImage Analysis Symposium (CBIAS) 2022 - a review

Posted by Stefania Marcotti, on 14 December 2022

Did you want to participate in the Crick BioImage Analysis Symposium (CBIAS) but missed it? Are you planning to join us next year for CBIAS2023 but unsure if it would be relevant for you? We’ve asked three of this year’s participants to tell us about their experience and collated their reports here! We’ll hear from

Microscopy in Africa – an interview with Michael Reiche

Posted by Helen Robertson, on 29 July 2022

We talk with Michael Reiche about the recently launched African Microscopy Inititiative and two other imaging-related programmes in Africa that he is overseeing

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Microscopy-related articles from our journals

Efficient and rapid fluorescent protein knock-in with universal donors in mouse embryonic stem cells Development 2023 150: dev201367
Direct fluorescent labeling of NF186 and NaV1.6 in living primary neurons using bioorthogonal click chemistry J Cell Sci 2023 136: jcs260600
An automated microscopy workflow to study Shigella–neutrophil interactions and antibiotic efficacy in vivo Disease Models & Mechanisms 2023 16: dmm049908

Microscopy-related preprint highlights

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Microscopy-related articles from our journals

Microscopy-related preprint highlights

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