Inputs and Outputs of vEM in a Sensory System

Posted by , on 19 May 2023

by Federica Mangione, The Francis Crick Institute, UK DOI: 10.1242/focalplane.14809 Challenge The sense of touch enables organisms to interact with their environment by perceiving physical forces and guiding complex behaviors. Touch sensing is mediated by sensory neurons that innervate the body surface of animals and, together with surrounding cells, form specialized structures known as tactile

How volumeEM (vEM) can help map neuronal circuits

Posted by , on 2 March 2022

by Nadine Randel, University of Cambridge, UK DOI:10.5281/zenodo.6320414 Challenge The nervous system processes sensory information and generates different behavioural outputs accordingly. Synaptic resolution wiring diagrams form a basis for our understanding of how the brain works. Such a connectome provides the synaptic connectivity between all neurons and allows to identify all potential neuronal pathways which

Meet the people behind Volume EM community (part 2)

Posted by , on 28 December 2021

In this second post, we continue talking with some of the scientists involved in the Volume EM initiative. If you missed the first part of these series of interview, you can find it here. Raffa Carzaniga and Errin Johnson, Training Working Group What are the aims of your WG? The main aim of the vEM

Meet the people behind Volume EM community (part 1)

Posted by , on 21 December 2021

Volume Electron Microscopy or volume EM (vEM) is a relatively new term that brings together several recently developed imaging approaches that use scanning and transmission electron microscopy (SEM and TEM) to allow the interrogation of cell and tissue ultrastructure in 3D, at μm to mm volume scales and nm resolutions.​ In this blog series ‘volume