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JCS snapshot - Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation

Posted by FocalPlane, on 12 January 2026

In our latest JCS snapshot we hear from Anne Müsch, who, together with David Cohen and Francisco Lázaro-Diéguez, discovered that bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation.

Imaging spotlight: Lock-in-SIM

Posted by FocalPlane, on 8 January 2026

In this paper highlight from Wenjie Liu and colleagues, we learn about Lock-in-SIM, a new methodology for structured illumination microscopy.

Damage done, tubules on - Studying membrane damaged-induced lysosomal tubulation

Posted by talcualmal, on 11 December 2025

In this post, I'll told you the "ins and outs" of our last publication in JCB about lysosomal tubulation in response to damage.

Epithelial Mechanics Fan Club

Posted by FocalPlane, on 4 December 2025

In this post, Nimesh Chahare and Julia Eckert tell us about the 'Epithelial Mechanics Fan Club'. You can follow the club on Bluesky, X, and now on their new website. Reach out to Nimesh and Julia if you would like to contribute.

JCS snapshots: the cilia and flagella edition

Posted by FocalPlane, on 24 November 2025

Journal of Cell Science recently published a Special Issue on Cilia and Flagella: from Basic Biology to Disease, edited by Pleasantine Mill and Lotte Pedersen. We invited the authors of the research published in this issue to produce JCS snapshots, short videos highlighting the key findings from their papers. Below, you can find the snapshots

JCS Special Issue - 'Cilia and Flagella: from Basic Biology to Disease'

Posted by FocalPlane, on 10 November 2025

We'll be celebrating the research published in JCS's special issue on cilia and flagella with the UK Cilia and Centrosome Network at their upcoming symposium on Tuesday 25 November.

FocalPlane features... membrane trafficking recordings

Posted by FocalPlane, on 10 November 2025

In September, we hosted a special online symposium together with the Membrane Trafficking webinar series, organised by Francesca Bottanelli, Felix Campelo and Ishier Raote. The webinar featured short talks from Nick Ader (UNC Greensboro), Hannes Maib (University of Sheffield) and Mónica Quiñones-Frías (Brandeis University), followed by a keynote lecture from Gillian Griffiths (Yale University. You can view the recordings of

FocalPlane features... preLights recording

Posted by FocalPlane, on 25 September 2025

In our FocalPlane features... preLights webinar, Felipe Del Valle Batalla and Vibha Singh presented live preLights highlighting preprinted research from Carmen Rodilla-Ramírez, Francesca Bottanelli and colleagues on the link between T-cell protrusions and CAR signalling, and from Eva Mejía-Ramírez, Carolina Florian and colleagues on the role of RhoA in stem cell ageing

Microscopy preprints – applications in biology

Posted by FocalPlane, on 19 September 2025

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.

JCS snapshot - TMEM184B modulates endolysosomal acidification via the vesicular proton pump

Posted by FocalPlane, on 17 September 2025

In our latest JCS snapshot we hear from Elizabeth Wright, who, together with Martha Bhattacharya and colleagues, discovered that TMEM184B modulates endolysosomal acidification via the vesicular proton pump. In this snapshot, Elizabeth takes us through the key findings from their research.

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Microscopy-related articles from our journals

Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface J Cell Sci 2025 138: jcs264154
The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential Development 2025 152: dev204661
The short isoform of Tango1 is dispensable for zebrafish survival but is required for skeletal patterning and integrity Biology Open 2025 14: bio062117

Microscopy-related preprint highlights

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Microscopy-related articles from our journals

Microscopy-related preprint highlights

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