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Displaying posts with the tag: is_archive

Microscopy preprints – new tools and techniques in imaging

Posted by , on 20 September 2024

Here is a curated selection of preprints posted recently on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!

Featured image with Marina Schernthanner

Posted by , on 16 August 2024

Our featured image, acquired by Marina Schernthanner, shows the hair follicles of a young (postnatal day 9) C57B6 mouse’s back skin. By using ethanol-based tissue clearing, Mariana stained fixed whole-mount tissue samples of the murine skin after removing the surface haircoat and subcutaneous fat layer. LYVE-1 (orange) marks the lymphatic vasculature, Keratin-14 (red) highlights the

Featured image with Thibault Dhellemmes and Jérémie Teillon

Posted by , on 1 March 2024

Our featured image shows the full morphology of Relaxin-3 neurons in an entire adult mouse brain. To observe the full depth of this brain, it was made transparent by applying an optical clearing technique called Adipoclear. The sample was observed on an Ultramicroscope II light sheet microscope and is a maximum intensity projection over the

Featured image with Virginia Barrera

Posted by , on 2 February 2024

Our featured image was acquired by Virginia Barrera and was the winning image from the Institute of Molecular and Cellular Biology of Rosario (IBR-CONICET) annual retreat. It depicts a transversal cut of a soybean, with Calcofluor White staining cellulose and Basic Fuchsine labelling lignin.

Tissue clearing: what invisible samples reveal about biology

Posted by , on 8 September 2021

Written by Jorge Almagro and Hendrik Messal The tissues that constitute organs exist in our body in 3D. However, for practical reasons, histological analysis has been traditionally performed in 2D, slicing a few micrometer-thick sections to analyse them under the microscope. While this has been critical to understand our anatomy for centuries, it constitutes a simplification of