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New insights into corneal development from vEM

Posted by , on 17 June 2025

by Rob Young*, Kiranjit Bains*, Phil Lewis* and Andrew Quantock* *Biophysics Research Group, School of Optometry & Vision Sciences, Cardiff University, UK Challenge The unique transparency of corneal stromal tissue, essential for vision, is dependent upon the remarkable order of component collagen fibrils, which exhibit highly uniform diameter, spacing and orientation. However, processes involved in
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International Microscopy Facility Survey

Posted by , on 9 November 2024

Some of you may have seen this already (thanks if you have already filled this in). I have been running an International Microscopy Facility Survey over the last few months. It is based on the excellent BioImaging UK survey that was published a few years ago, but with an extended focus to include Optical Microscopy,
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vEM reveals the cellular composition of the Blood Nerve Barrier

Posted by , on 11 October 2024

Using Serial Block-Face-SEM6 and AT-SEM, we characterized the cellular composition and interactions along EndoBVs7. Unlike the BBB, we observed that the vasculature within the endoneurium is not completely covered. Upon closer examination of the cells in contact with EndoBVs, we identified three distinct cell types frequently interacting with the vasculature.
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And the winner is…

Posted by , on 7 June 2024

In an exciting turn of events, we are delighted to announce that the winner of the FocalPlane/elmi (European Light Microscopy Initiative) is the electron micrograph, ‘Glorious Lymphocyte’ from Rossana Melo! The image shows a leukocyte (lymphocyte) trapped among aggregates of red blood cells in a small lung vessel of a patient with asthma. The image
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FocalPlane features... microscopy-based outreach

Posted by , on 11 March 2024

The first webinar of our new series of FocalPlane features... focussed on microscopy-based outreach. We hosted fantastic talks from Paola Moreno-Roman from Foldscope Instruments and Martin Jones from The Francis Crick Institute and we share the recordings here.
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An interview on the Traversing European Coastlines (TREC) project with Yannick Schwab

Posted by , on 5 March 2024

Traversing European Coastlines (TREC) is a flagship project in the planetary biology theme from European Molecular Biology Laboratory (EMBL). A consortium of several research organisations under the lead of EMBL has embarked on an expedition to sample the biodiversity in the coastlines of Europe in 2023 and 2024. We caught up with Yannick Schwab, Team
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Imaging with the Instituto Gulbenkian de Ciência’s Electron Microscopy Facility

Posted by , on 14 December 2023

In our ‘Imaging with…’ blog post, we meet the staff of the Electron Microscopy (EM) facility at the Instituto Gulbenkian de Ciência, Lisbon, Portugal.
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An interview with Gabriela Casanova

Posted by , on 5 October 2022

MiniBio: Gabriela Casanova is Head of the Electron Microscopy Unit at the Faculty of Sciences of the Universidad de la República in Montevideo, Uruguay, a member of the executive committee of LABI, and president of the Uruguayan Society of Microscopy and Imaging (Sociedad Uruguaya de Microscopía e Imagenología). In 1979 she began her studies in
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An interview with Virginia Albarracin

Posted by , on 13 September 2022

MiniBio: Virginia Albarracin is the Head of the Centre for Electron Microscopy of the National University of Tucumán and CONICET in Tucuman, Argentina, as well as a group leader focusing on investigating extremophiles. Virginia studied her BSc degree in Biology, and PhD degree in Biochemistry at the University of Tucuman, Argentina. During her PhD she
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Turbo mini-bios

Posted by , on 19 July 2022

MiniBio: The Electron Microscopy Unit at the Faculty of Sciences in Universidad de la Republica is led by Dr. Gabriela Casanova (see interview in Latin American Microscopists series). In this special issue we include turbo mini-bios highlighting the work and career of unit members and main collaborators, including Dr. Magela Rodao, Gaby Martinez, Ana Laura
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