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From Click to Code: Reproducibility in Bio-image Analysis

Posted by , on 5 August 2025

Reproducibility is at the heart of good science. But when it comes to bio-image analysis, it can feel difficult to achieve. Complex datasets, shifting software environments, and countless manual tweaks often make it hard to retrace your own steps and share workflows with others. An aim should be to package the entire analysis, like code, data
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Illuminating the Brain: Microscopy Techniques in Neuroscience and My Applications in the Lab

Posted by , on 23 June 2025

Understanding the brain’s complexity requires more than theory or behaviour; it demands a look at the smallest units of structure and function. Microscopy has long been a cornerstone of neuroscience, evolving rapidly from conventional optical methods to cutting-edge super-resolution and electron techniques. This article explores how confocal microscopy, STORM, and electron microscopy are advancing our
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Microscopy Meets Medicine: Spirulina-Derived Nanoparticles Take Aim at Cancer

Posted by , on 14 April 2025

This article from the International Journal of Nanomedicine presents a promising new biomimetic strategy that makes use of natural resources as an alternative in cancer therapy. The Researchers have created Spirulina-derived Nanoparticles (sNPs) using a solvent-free process and with the aid of centrifugation and sonication technique. The lysosomes sus-pended averaged an approximate size of 126nm,
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Microscopy preprints - applications in biology

Posted by , on 4 April 2025

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Announcing our 2025 FocalPlane correspondents

Posted by , on 24 February 2025

We are delighted to welcome our latest correspondents to the FocalPlane community. We are looking forward to working with Sally Horton, Varsha Mahapatra and Nicole Noel throughout 2025 and can’t wait to read their blog posts! Sally is a postdoctoral fellow at The Francis Crick Institute in London, UK. At The Crick, her research focusses
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Microscopy preprints - applications in biology

Posted by , on 21 February 2025

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Featured image with Amy Engevik

Posted by , on 14 February 2025

Our featured image, acquired by Amy Engevik, shows a differentiated intestinal organoid from a germline Myosin 5b knockout mouse.
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Microscopy preprints - new tools and techniques in imaging

Posted by , on 7 February 2025

Here is a curated selection of preprints posted recently on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!
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Enter the Node-FocalPlane image competition

Posted by , on 5 February 2025

To accompany the Biologists @ 100 conference, we are launching the Node–FocalPlane image competition. Enter your best biological research images for your chance to win £250.
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Microscopy preprints - bioimage analysis

Posted by , on 24 January 2025

Here is a curated selection of preprints published recently. In this post, we focus specifically on bioimage analysis and data management.
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