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Featured image with Aswathy G Krishnan

Posted by FocalPlane, on 10 October 2025

Our featured image, acquired by Aswathy G Krishnan, depicts a neural rosette of a cerebral organoid derived from human induced pluripotent stem cells (hiPSC). The organoids were collected, fixed, dehydrated, embedded in tissue freezing media and cryosectioned at 20 µm thickness. Then, the sections were immunolabelled and imaged under confocal microscope at 60X magnification. The

FocalPlane features... preLights recording

Posted by FocalPlane, on 25 September 2025

In our FocalPlane features... preLights webinar, Felipe Del Valle Batalla and Vibha Singh presented live preLights highlighting preprinted research from Carmen Rodilla-Ramírez, Francesca Bottanelli and colleagues on the link between T-cell protrusions and CAR signalling, and from Eva Mejía-Ramírez, Carolina Florian and colleagues on the role of RhoA in stem cell ageing

Introducing SciCommConnect three-minute talk winner Oliver Anderson

Posted by Helen Zenner, on 7 August 2024

In June, the Node, preLights and FocalPlane hosted SciCommConnect, a science communication event focussed on learning new scicomm skills and networking with like-minded researchers. As part of the day, we hosted a three-minute research talk competition, and we were treated to 12 fantastic talks on a range of topics. We had two competition winners, Oliver

Asymmetric cell divisions in 3 dimension stem cell colonies

Posted by Agathe Chaigne, on 27 September 2021

When looking at the development of a multicellular organism, for example a human, the first striking feature is the progressive increase in cell numbers due to successive divisions, from one single tiny cell 80 mm in diameter to a 3.5 kg ball of organised cells forming a new-born baby. The way cells divide, in particular

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Microscopy-related articles from our journals

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples Development 2024 151: dev202307
filoVision – using deep learning and tip markers to automate filopodia analysis J Cell Sci 2024 137: jcs261274
C omputational tools for quantifying actin filament numbers, lengths, and bundling Biology Open 2024 13: bio.060267

Microscopy-related preprint highlights

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