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Microscopy preprints – new tools and techniques in imaging

Posted by , on 20 February 2026

Here is a curated selection of the latest preprints on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!
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JCS snapshot: Suppressing microtubule detyrosination augments AAV2 endosomal escape & gene delivery

Posted by , on 19 February 2026

In our latest JCS snapshot we hear from Shefali Tripathi, who, together with Nitin Mohan, Giridhara Jayandharan and team, found that suppressing microtubule detyrosination augments adeno-associated virus 2 endosomal escape and gene delivery.
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Featured image with Jan Martinek

Posted by , on 13 February 2026

Our featured image is a spinning disk fluorescence micrograph, acquired by Jan Martinek, showing an Arabidopsis thaliana root that formed a spiral on a forgotten Petri dish lying flat on the bench. In this orientation, the root cannot grow downward gravitropically, so it keeps turning.
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JCS snapshot: RNP1A regulates cell shape in Dictyostelium amoebas

Posted by , on 12 February 2026

In our latest JCS snapshot we hear from Mark Jacob, who, together with Yinan Liu, Douglas Robinson and team, found that the RNA-binding protein RNP1A regulates cell shape in Dictyostelium amoebas. In this snapshot, Mark takes us through the key findings from their research.
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Imaging spotlight - How to divide without a ring: a mechanical ratchet drives unilateral cytokinesis

Posted by , on 10 February 2026

In this paper highlight, Jan Brugués and Alison Kickuth discuss the microscopy and microrheology techniques that they used in their research dissecting the mechanics of cytokinesis.
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Workshop report: EMBO Course on Image Processing in Cryo-EM

Posted by , on 9 February 2026

Freya Cardozo shares her workshop report from the EMBO course on Imaging Processing in Cryo-EM. Freya's attendance was supported with a JCS-FocalPlane Training Grant.
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Microscopy preprints: bioimage analysis

Posted by , on 6 February 2026

Here is a curated selection of preprints published (or updated) recently. In this post we focus specifically on bioimage analysis and data management.
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Imaging spotlight: ShapeSpaceExplorer

Posted by , on 5 February 2026

In this paper highlight, we learn about ShapeSpaceExplorer, a tool for measuring cell shape of migrating cells, developed by Samuel Jefferyes, Anne Straube and colleagues.
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Funding to access UK Euro-BioImaging services: next round closes on 31 March!

Posted by , on 4 February 2026

The next round of applications is open for the UK Bioimaging User Access Fund, which provides UK researchers with access to state-of-the-art bioimaging technologies and analysis services at the UK Node of Euro-BioImaging. What’s Available: The UK Node comprises 14 facilities across 7 leading UK sites*, offering open access to a wide range of advanced
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Workshop report: York Confocal Microscopy course

Posted by , on 3 February 2026

During the four-day Confocal Microscopy 2025 course at the University of York, I gained a better understanding of both the fundamentals of microscopy and more advanced techniques. The daily schedule consisted of the introduction of the relevant topics in the morning, followed by several hands-on practical sessions. In these, we were split into small groups
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