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The Company of Biologists Workshop - Membrane Function: Insights from Cellular Diversity and Evolution

Posted by FocalPlane, on 28 September 2026

Applications are open for early-career researchers to apply for funded places to attend this Workshop.

FocalPlane features... cell migration recordings with Ankita Jha, Raphaël Clément and Katrina Velle

Posted by FocalPlane, on 25 September 2026

On 17 September 2026, we held the second webinar in our FocalPlane features… series on emergent models and quantitative analysis of cell migration, organised by Pablo J. Sáez and Valeria Venturini. In this webinar, we heard from Ankita Jha on ‘Decoding bleb driven signaling in cancer disease progression’, Raphaël Clément on ‘Navigating without neurons or

Featured image with Ádám Soós

Posted by FocalPlane, on 25 September 2026

Our featured image, acquired by Ádám Soós is titled “Guided by GDNF: enteric neural crest cells weaving the future gut nervous system.” It shows enteric neural crest-derived cells streaming out from an embryonic day 6 chicken midgut explant, forming an interconnected migratory network on a fibronectin-coated surface. The culture was exposed to 20 ng/ml GDNF,

Register now for FocalPlane features... quantitative plant imaging

Posted by FocalPlane, on 23 September 2026

In this webinar, we'll hear from Marcel Dickmanns on 'Exploring the Molecular Landscape within Plant Cells by Cryo-Electron Tomography' and Laura Copeland on 'Multimodal Quantitative Fourier Ptychographic Microscopy and Fluorescence Imaging Reveals Stable Bacterial Colonisation Architecture Under Phosphate Limitation'.

Imaging spotlight: linking mechanical forces and the Golgi

Posted by FocalPlane, on 22 September 2026

In this Imaging spotlight, Felix Campelo, Stéphanie Miserey and Jean-Baptiste Manneville highlight the key findings from their research asking whether the Golgi apparatus can sense and respond to mechanical forces. They talk about the importance of selecting the correct microscope for your question rather than assuming that the most sophisticated microscopy is best, as well

Microscopy preprints – new tools and techniques in imaging

Posted by FocalPlane, on 18 September 2026

Here is a curated selection of the latest preprints on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!

Featured image with Elena Nicolay

Posted by FocalPlane, on 11 September 2026

Our featured image, acquired by Elena Nicolay, shows double-transgenic zebrafish larvae in a Pop Art-style collage, with macrophages and neurons depicted in different colours.

Imaging spotlight: FOCUS-3D

Posted by FocalPlane, on 10 September 2026

In this Imaging spotlight, Qinghua Zhang, Joaquín Navajas Acedo, Guoqiang Yu and team introduce FOCUS-3D, a tool for segmenting cells from 3D fluorescence microscopy images. We learn what's different about FOCUS-3D and how the researchers made it useful and usable for a wide-range of biologists.

Imaging spotlight: Live imaging reveals epithelial cell extrusion in a sea anemone

Posted by Ines Fournon-Berodia, on 7 September 2026

In this Imaging spotlight, Inés Fournon Berodia and colleagues share how live confocal imaging and machine-learning-assisted image analysis revealed epithelial cell extrusion in the sea anemone Nematostella vectensis.

Microscopy preprints: bioimage analysis

Posted by FocalPlane, on 4 September 2026

Here is a curated selection of preprints published or updated recently. In this post we focus specifically on bioimage analysis and data management.

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Microscopy-related articles from our journals

Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface J Cell Sci 2025 138: jcs264154
The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential Development 2025 152: dev204661
The short isoform of Tango1 is dispensable for zebrafish survival but is required for skeletal patterning and integrity Biology Open 2025 14: bio062117

Microscopy-related preprint highlights

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