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FocalPlane features… Laura Bacete and Sven Truckenbrodt

Posted by FocalPlane, on 5 August 2026

View the recordings from our second webinar on quantitative plant imaging. We heard from Laura Bacete, on ‘Brillouin Microscopy for Quantitative Analysis of Plant Cell Wall Mechanics Across Systems’ and Sven Truckenbrodt on ‘PlantEx: multicolour super-resolution imaging of plants with expansion microscopy’.

Featured image with Saheli Roy

Posted by FocalPlane, on 3 August 2026

Our featured image, acquired by Saheli Roy, depicts a maximum intensity projection of a female Drosophila melanogaster‘s reproductive system – both ovaries, lateral and common oviducts, uterus and seminal receptacle (an organ for sperm storage that allows the female fly to control fertilization). The ovaries are full of auto-fluorescent developing and mature eggs, because the

Microscopy preprints: bioimage analysis

Posted by FocalPlane, on 24 July 2026

Here is a curated selection of preprints published or updated recently. In this post we focus specifically on bioimage analysis and data management.

JCS snapshot: A ULK1–MTFR1L feedback loop links mitochondrial fission, mitophagy and apoptosis

Posted by FocalPlane, on 22 July 2026

In our latest JCS snapshot we hear from Riccardo Babic, Leon Lucya and Christoph Reiter, who, together with Claudine Kraft and team, identified a ULK1–MTFR1L feedback loop that links mitochondrial fission, mitophagy and apoptosis.

Pearling and directed trafficking as determinants of mitochondrial genome organization and network architecture

Posted by FocalPlane, on 21 July 2026

In this highlight, we hear from Juan C. Landoni, who discusses his recent work uncovering how mitochondria distribute their genome through pearling (Landoni et al. 2026, Science), and the key role of mitochondrial trafficking in maintaining new material dissemination and network architecture (Winter, Landoni et al. 2026, JCB).

Featured image with Manomay Pawar

Posted by FocalPlane, on 20 July 2026

Our featured image, acquired by Manomay Pawar, depicts MDA-MB-231 triple negative breast cancer cells treated with drug Bemcentinib (R428), a small molecule inhibitor of AXL (a receptor tyrosine kinase) and labelled with phalloidin (actin;green), anti-Paxillin antibody to mark focal adhesions (magenta) and DAPI (DNA;yellow). The white coloured puncta represent colocalisation of paxillin with the ends

Microscopy preprints: applications in biology

Posted by FocalPlane, on 15 July 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.

Imaging spotlight: VLab4Mic

Posted by FocalPlane, on 7 July 2026

In this preprint highlight, Damián Martínez, Bruno M. Saraiva, Mario Del Rosario, Ricardo Henriques introduce VLab4Mic, an open-source simulation platform that allows researchers to optimise microscopy experiments before performing them.

Journal of Cell Science Special Issue: Cell Biology of the Nucleus

Posted by FocalPlane, on 6 July 2026

Journal of Cell Science’s special issue on the cell biology of the nucleus is now complete. In their Editorial, Megan King and Abby Buchwalter discuss the themes of the special issue, including the connections between the nucleus and cytoskeleton, nuclear mechanics, nuclear lipids, the nuclear pore complex and nuclear transport, the nuclear lamina, chromatin and

Featured image with Joan Roncero Carol

Posted by FocalPlane, on 3 July 2026

Our featured image, acquired by Joan Roncero Carol, shows two mouse preimplantation blastocysts at E4.5 showing immunofluorescence staining against LAMP1 to visualize lysosomal distribution at this developmental stage, together with phalloidin staining to clearly outline cell membranes.

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Microscopy-related articles from our journals

Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface J Cell Sci 2025 138: jcs264154
The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential Development 2025 152: dev204661
The short isoform of Tango1 is dispensable for zebrafish survival but is required for skeletal patterning and integrity Biology Open 2025 14: bio062117

Microscopy-related preprint highlights

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