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Microscopy preprints – new tools and techniques in imaging

Posted by FocalPlane, on 3 April 2026

Here is a curated selection of the latest preprints on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!

The NFDI4BIOIMAGE Research Data Management Community Survey 2026

Posted by Lisa Schaefer, on 2 April 2026

German BioImaging, within its work in the NFDI4BIOIMAGE consortium, and in collaboration with Euro-BioImaging ERIC, has launched the NFDI4BIOIMAGE Research Data Management Community Survey 2026. The survey aims to better understand how bioimaging data are generated, processed, managed, and shared across the life sciences community.

Imaging spotlight: Minimally invasive live tissue clearing with SeeDB-Live

Posted by Takeshi Imai, on 1 April 2026

In this paper highlight from Shigenori Inagaki and Takeshi Imai, we learn about SeeDB-Live, a methodology for applying tissue clearing to live-cell imaging.

New webinar series on plant imaging

Posted by FocalPlane, on 30 March 2026

To build on the momentum of our recent Workshop, Macro to micro: quantitative plant imaging across scales, we are launching a new webinar series together with Workshop organisers Alex Johnson (University of Exeter) and Joe McKenna (Warwick University). We’ll be hosting quarterly webinars allowing researchers from all career stages to showcase their research on plant

Featured image with Nat Prunet

Posted by FocalPlane, on 27 March 2026

Our featured image from Nat Prunet is a composite image of pollen grains from various plant species. Each pollen grain was imaged separately for red autofluorescence with super-resolution Airyscan on a Zeiss LSM 980 microscope. 3D datasets were processed on Fiji with edge-finding and color-coding for depth.

Imaging spotlight: dissecting the precancerous niche

Posted by FocalPlane, on 25 March 2026

In this paper highlight we hear from Greta Skrupskelyte and Maria Alcolea, who discuss their recent paper dissecting the role of the microenvironment and tumour-stromal communication in tumour growth and survival.

Microscopy preprints: bioimage analysis

Posted by FocalPlane, on 20 March 2026

Here is a curated selection of preprints published (or updated) recently. In this post we focus specifically on bioimage analysis and data management.

Imaging with... ADMiRA

Posted by FocalPlane, on 16 March 2026

In our ‘Imaging with…’ blog post, we meet the team at ADMiRA, the Advanced Microscopy Applications Unit at the National Cancer Institute in Mexico City.

Featured image with Julia Zheku

Posted by FocalPlane, on 13 March 2026

Our featured image, acquired by Julia Zheku, depicts a maize (corn) cross section, with a developing nodal root dynamically breaking through the basal stem node which is typically found below the soil surface. Such a root is not visible while sectioning, making this a beautiful, yet lucky, image. The section was prepared by mounting the

Spider-like neurons finding their way: signposts for multipolar migration in the developing brain

Posted by Jaakko Lehtimäki, on 11 March 2026

Developing neurons travel large distances and orchestrate into precise layers to enable functional wiring of the brain. Within this unique tissue environment, many neurons use their neighbors like railway tracks, navigating in a directed manner toward their correct layer. However, this is not always the case. Multipolar migration, where cells extend multiple protrusions and display

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Microscopy-related articles from our journals

Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface J Cell Sci 2025 138: jcs264154
The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential Development 2025 152: dev204661
The short isoform of Tango1 is dispensable for zebrafish survival but is required for skeletal patterning and integrity Biology Open 2025 14: bio062117

Microscopy-related preprint highlights

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