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Featured image with Subhajit Karmakar

Posted by , on 11 April 2025

Our featured image, acquired by Subhajit Karmakar, depicts a dividing MDA-MB-231 cancer cell that has been stained to visualise the localisation of two key proteins: CK2, a highly oncogenic kinase, and an E3 ligase, a tumour suppressor.
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Microscopy preprints - applications in biology

Posted by , on 4 April 2025

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Announcing the winners of the Node–FocalPlane image competition.

Posted by , on 27 March 2025

We are delighted to announce the winners of the Node–FocalPlane image competition, which we presented at the Biologists @ 100 conference, as well as on the Node and FocalPlane. In first place is ‘Cell-estial bloom’ from Özge Özgüç. Özge’s image is a colony of live hiPSCs, with fluorescently labelled Lamin B delineating the nuclear lamina
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Microscopy preprints – new tools and techniques in imaging

Posted by , on 21 March 2025

Here is a curated selection of preprints posted recently on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!
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Biologists @ 100 video guide

Posted by , on 17 March 2025

It’s only one week to go until the start of the Biologists @ 100 conference and we’re looking forward to welcoming you in Liverpool. Together with our sister community sites, the Node and preLights, we’ve made a recording to give you a flavour of what to expect during the conference.
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Featured image with Omkar Joshi

Posted by , on 14 March 2025

Our featured image, acquired by Omkar Joshi, showcases a U2OS cell immunostained for paxillin (green), TOMM20 (mitochondria, white), and F-actin (labelled using SiR-Actin, magenta), with DAPI (yellow) marking the nucleus.
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Vote for your favourite image

Posted by , on 11 March 2025

We are delighted to unveil the shortlisted images in the Node–FocalPlane image competition. Thanks to everyone that entered, we received so many fantastic images and congratulations to all the finalists. You can vote for your favourite image using the poll at the bottom of the page.
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Microscopy preprints - bioimage analysis

Posted by , on 7 March 2025

Here is a curated selection of preprints published recently. In this post, we focus specifically on bioimage analysis and data management.
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ScanR workshop report

Posted by , on 3 March 2025

In mid-August 2024, I had the fantastic opportunity of attending the ScanR workshop; held at the Institute of Biophysics in Brno, Czech Republic and organised by world-leading experts who have been using this technology for >10 years. Being renowned as the birthplace of the father of genetics, Gregor Johann Mendel, the location was also special,
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Featured image with Anthony Dornan and Fara van der Schans

Posted by , on 28 February 2025

Our featured image, acquired by Anthony Dornan and Fara van der Schans, showcases the perinuclear distribution of mitochondria in the highly respiratory human pancreatic ductal adenocarcinoma (PDAC) tumour cells (Panc-1) stained with the mitochondrial stain TMRE (thermal LUT), the mitochondria are associated with the nuclei, stained with DAPI (cyan). The live cell image is a maximum intensity Z-projection generated
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