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Microscopy preprints - bioimage analysis

Posted by , on 22 August 2025

Here is a curated selection of preprints published recently. In this post, we focus specifically on bioimage analysis and data management.
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FocalPlane features... meets preLights

Posted by , on 20 August 2025

For our second collaborative FocalPlane features… webinar we have teamed up with preLights, our sister community site. This webinar will be hosted by Felipe Del Valle Batalla (University of Edinburgh, UK) and Vibha Singh (Princess Margaret Cancer Research Tower (UHN), Canada), two members of the preLights community (known as preLighters), who have selected two recent
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Featured image with Ludovica Altieri

Posted by , on 15 August 2025

Our featured image, acquired by Ludovica Altieri, shows murine primary cortical neurons developing interconnections. The cells are stained for neuronal tubulin (TUJI antibody, cyan) and DNA (DAPI, blue). Cultures were prepared by dissecting cortices from mouse embryos (E18), then mechanically dissociating single cells for plating. Explanted primary neurons placed in culture regress several stages back,
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Microscopy preprints - applications in biology

Posted by , on 12 August 2025

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Featured image with Krystyna Gieniec

Posted by , on 1 August 2025

Our featured image, 'Unexpected guests' acquired by Krystyna Gieniec, is a 2D culture of mouse mammary fibroblasts stained for Acta2 (magenta) and Vimentin (gold), with some contaminating epithelial cells stained for pan-Cytokeratin (cyan). The image was acquired using a Leica Stellaris 8 confocal microscope.
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Reflecting on five years of FocalPlane

Posted by , on 30 July 2025

We are celebrating FocalPlane’s fifth birthday following its launch in 2020. The idea of launching a microscopy community site came from discussions between Journal of Cell Science’s (now former) Executive Editor Sharon Ahmad and Sean Munro, Head of Cell Biology at the MRC Laboratory of Molecular Biology, Cambridge and a Company Director at The Company
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Microscopy preprints - new tools and techniques in imaging

Posted by , on 25 July 2025

Here is a curated selection of preprints posted recently on new tools and techniques in imaging. Let us know if we are missing any recent preprints that are on your reading list!
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Bridging AI and Super-Resolution Microscopy: Highlights from the AI4Life Workshop & Hackathon at SMLMS 2024

Posted by , on 22 July 2025

In the days leading up to the Single Molecule Localization Microscopy Symposium (SMLMS) 2024, AI4Life hosted the Pre-symposium AI4Life Workshop & Hackathon: Trends in AI for Super-Resolution Microscopy at the Instituto Gulbenkian de Ciência (IGC) (now Gulbenkian Institute for Molecular Medicine (GIMM)) in Portugal. The event brought together an interdisciplinary group of leading and early-career researchers
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Exploring the Microcosmos through Foldscope-Frugal Science Microscopy in Focus

Posted by , on 18 July 2025

The third annual iteration of the Lodha Genius Programme at Ashoka University, Sonepat, featured a month-long workshop series for students of grades 9 and 10, introducing them to the intricate diversity of the microscopic world through the use of a frugal science innovation—the Foldscope. Much like the initiative described in this article on IndiaBioscience, this
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Featured image with Maik Bischoff

Posted by , on 18 July 2025

Our featured image, acquired by Maik Bischoff, captures a portion of the testis from the fruit fly Drosophila hydei. Like all insect testes, it is enveloped by a muscle layer. F-actin was stained using phalloidin, making the muscle fibers visible, while DAPI staining revealed the multiple nuclei within each syncytial myotube. An antibody against Drosophila
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