Cell migration - FocalPlane

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Featured image with Maik Bischoff

Posted by FocalPlane, on 18 July 2025

Our featured image, acquired by Maik Bischoff, captures a portion of the testis from the fruit fly Drosophila hydei. Like all insect testes, it is enveloped by a muscle layer. F-actin was stained using phalloidin, making the muscle fibers visible, while DAPI staining revealed the multiple nuclei within each syncytial myotube. An antibody against Drosophila

Featured image with Hoang Anh Le

Posted by FocalPlane, on 5 July 2024

Our featured image, acquired by Hoang Anh Le, shows an Ewing’s sarcoma cancer cell plated on a fibronectin-coated surface. The cell was fixed with 4% formaldehyde and stained using phalloidin (white) and DAPI (in pink). The sample was imaged using a confocal Zeiss 880 microscope with Airyscan.

Featured image with Sujan Ghimire

Posted by FocalPlane, on 26 April 2024

Our featured image, acquired by Sujan Ghimire, shows a U2OS cell stained for paxillin (Cyan Hot) and actin (Red Hot) following an immunofluorescence staining protocol. The image was captured using structured illumination microscopy (SIM) with Deltavision OMX (63x Oil, NA: 1.42) at Cell Imaging and Cytometry facility, Turku Bioscience.

An interview with Pablo J. Sáez

Posted by Mariana De Niz, on 17 January 2023

MiniBio: Dr. Pablo J. Sáez is a Professor at UniversitätsKlinikum Eppendorf (UKE), in Hamburg, Germany since 2020, where him and his lab study single and collective cell migration with a focus on immune cells. He was born in Chile and did his early career there. He did his BSc, MSc and PhD at Pontificia Universidad

Cell Worlds: meet the microscopists

Posted by FocalPlane, on 14 July 2022

February, 2022 saw the world premiere of the Cell Worlds documentary and exhibition. Cell Worlds was created by co-founders Renaud Pourpre and Terence Saulnier to bring microscopy out of the lab and display it in new ways to new audiences. Here, we focus on the team of microscopists who provided the images and movies.

Tumors want to break free! How knocking down Myo10 can change invasive properties of a breast cancer xenograft model.

Posted by FocalPlane, on 16 December 2021

This is one of the research highlights from our second preLights – FocalPlane social writing event. You can find the other reseach highlight in preLights. Myosin-X-dependent assembly of the extracellular matrix limits breast cancer invasion Emilia Peuhu, Guillaume Jacquemet, Colinda LGJ Scheele, Ilkka Paatero, Kerstin Thol, Aleksi Isomursu, Maria Georgiadou, Camilo Guzman, Satu Koskinen, Asta Laiho,

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Microscopy-related articles from our journals

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples Development 2024 151: dev202307
filoVision – using deep learning and tip markers to automate filopodia analysis J Cell Sci 2024 137: jcs261274
C omputational tools for quantifying actin filament numbers, lengths, and bundling Biology Open 2024 13: bio.060267

Microscopy-related preprint highlights

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