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Featured image with Shang-Wu Shih

Posted by , on 9 October 2026

Our featured image, acquired by Shang-Wu Shih, shows ionocytes distributed along the gill filaments of marine medaka. These specialized epithelial cells are responsible for maintaining systemic ion and acid–base homeostasis. Gill tissues were fixed and immunostained for Na⁺/K⁺-ATPase (NKA, red), a marker of ionocytes, and actin (green/cyan), which outlines the tissue architecture. Images were acquired
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Microscopy preprints: applications in biology

Posted by , on 5 October 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Featured image with Ádám Soós

Posted by , on 25 September 2026

Our featured image, acquired by Ádám Soós is titled “Guided by GDNF: enteric neural crest cells weaving the future gut nervous system.” It shows enteric neural crest-derived cells streaming out from an embryonic day 6 chicken midgut explant, forming an interconnected migratory network on a fibronectin-coated surface. The culture was exposed to 20 ng/ml GDNF,
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Imaging spotlight: FOCUS-3D

Posted by , on 10 September 2026

In this Imaging spotlight, Qinghua Zhang, Joaquín Navajas Acedo, Guoqiang Yu and team introduce FOCUS-3D, a tool for segmenting cells from 3D fluorescence microscopy images. We learn what's different about FOCUS-3D and how the researchers made it useful and usable for a wide-range of biologists.
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Imaging spotlight: Live imaging reveals epithelial cell extrusion in a sea anemone

Posted by , on 7 September 2026

In this Imaging spotlight, Inés Fournon Berodia and colleagues share how live confocal imaging and machine-learning-assisted image analysis revealed epithelial cell extrusion in the sea anemone Nematostella vectensis.
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Microscopy preprints: applications in biology

Posted by , on 21 August 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Seeing comes before knowing: how live imaging led to the discovery of blood vessel-resident macrophages

Posted by , on 12 August 2026

Bart Weijts and Catherine Robin share the behind the paper story on their discovery of blood vessel-resident macrophages.
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Microscopy preprints: applications in biology

Posted by , on 15 July 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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Featured image with Joan Roncero Carol

Posted by , on 3 July 2026

Our featured image, acquired by Joan Roncero Carol, shows two mouse preimplantation blastocysts at E4.5 showing immunofluorescence staining against LAMP1 to visualize lysosomal distribution at this developmental stage, together with phalloidin staining to clearly outline cell membranes.
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Microscopy preprints: applications in biology

Posted by , on 29 May 2026

Here is a curated selection of preprints published recently. In this post, we share preprints that use microscopy tools to answer questions in biology.
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