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Special Edition Virtual Pub: Open Hardware in Imaging

Posted by Marianna Poli, on 6 July 2023

Imaging technologies are becoming increasingly complex and ever more expensive, reducing the general accessibility and potential reach of cutting-edge techniques. Many scientists and companies are committed to making imaging hardware and software solutions openly available to a wide audience. The Special Edition Virtual Pub “Open Hardware in Imaging” in collaboration with the Euro-BioImaging Industry Board

Using an autocollimator to align 4f systems

Posted by Brian Patton, on 29 June 2022

Graeme Johnstone, Brian Patton, Department of Physics and SUPA, University of Strathclyde, Glasgow G4 0NG, United Kingdom Modern microscope systems comprise many optical elements with precise alignment tolerances. As such, as the complexity of the system increases, the challenge to align them rapidly becomes a major hurdle to implementing home-built designs. One recurring problem is

OpenFlexure: an open-source 3D printed microscope

Posted by Joe Knapper, on 19 October 2021

The OpenFlexure Microscope is an open-source microscope 3D printed in plastic, with versions suitable for hobbyists, researchers, and lab technicians. Currently used around the world as an accessible, customisable alternative to expensive and fixed commercial microscopes, the OpenFlexure Microscope began life as an academic prototype for holding a lens and sample in place. Here we

How I got into the Flamingo project, a new way of sharing custom-built light sheet microscopes

Posted by Michael Weber, on 12 October 2020

Sharing microscopy technology is crucial for biomedical research. This is the story how I joined Jan Huisken and his team to give other scientists quick access to custom-built light sheet microscopes.

“openFrame” for modular, extensible, easily maintained, open-source microscopy

Posted by Sunil Kumar, on 23 July 2020

The openFrame [1] is an open-source microscopy hardware project initiated by the Photonics Group in the Physics Department at Imperial College London that is intended to provide access to a modular, upgradable, easily maintained and modifiable microscope frame that can be implemented at relatively low cost compared to existing commercial instruments. openFrame is a component

Lessons learned from an open-hardware project in microscopy: The mesoSPIM initiative

Posted by Fabian Voigt, on 1 July 2020

The mesoscale selective plane illumination microscope (mesoSPIM) is a highly versatile open-source light-sheet microscope for imaging large (cm-sized) cleared tissue samples. Using the documentation and software available via mesospim.org and on Github, interested labs can set up their own microscope. Currently, ten mesoSPIM instruments are in operation around the globe and several more are under

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Microscopy-related articles from our journals

HCR spectral imaging: 10-plex, quantitative, high-resolution RNA and protein imaging in highly autofluorescent samples Development 2024 151: dev202307
filoVision – using deep learning and tip markers to automate filopodia analysis J Cell Sci 2024 137: jcs261274
C omputational tools for quantifying actin filament numbers, lengths, and bundling Biology Open 2024 13: bio.060267

Microscopy-related preprint highlights

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