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Imaging spotlight: linking mechanical forces and the Golgi

Posted by , on 22 September 2026

In this Imaging spotlight, Felix Campelo, Stéphanie Miserey and Jean-Baptiste Manneville highlight the key findings from their research asking whether the Golgi apparatus can sense and respond to mechanical forces. They talk about the importance of selecting the correct microscope for your question rather than assuming that the most sophisticated microscopy is best, as well
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Imaging spotlight: FOCUS-3D

Posted by , on 10 September 2026

In this Imaging spotlight, Qinghua Zhang, Joaquín Navajas Acedo, Guoqiang Yu and team introduce FOCUS-3D, a tool for segmenting cells from 3D fluorescence microscopy images. We learn what's different about FOCUS-3D and how the researchers made it useful and usable for a wide-range of biologists.
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Imaging spotlight: Live imaging reveals epithelial cell extrusion in a sea anemone

Posted by , on 7 September 2026

In this Imaging spotlight, Inés Fournon Berodia and colleagues share how live confocal imaging and machine-learning-assisted image analysis revealed epithelial cell extrusion in the sea anemone Nematostella vectensis.
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Imaging spotlight: CenSpark

Posted by , on 24 August 2026

In this Imaging spotlight, we hear about CenSpark, a small molecule probe for live imaging of centrioles, from Cédric Pourroy, Georgios Hatzopoulos, Pierre Gönczy and team.
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Seeing comes before knowing: how live imaging led to the discovery of blood vessel-resident macrophages

Posted by , on 12 August 2026

Bart Weijts and Catherine Robin share the behind the paper story on their discovery of blood vessel-resident macrophages.
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Imaging spotlight: FidlTrack

Posted by , on 10 August 2026

In this Imaging spotlight, we hear from Pierre Parutto and Edward Avezov about FidlTrack, a method for benchmarking and optimising single particle tracking.
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Imaging spotlight: fluorogenic L-DNA probes

Posted by , on 6 August 2026

In this Imaging spotlight, we hear from Bas van Bommel and Helge Ewers about the fluorogenic L-DNA probes they used to optimise DNA-PAINT labelling for single molecule localisation microscopy.
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Pearling and directed trafficking as determinants of mitochondrial genome organization and network architecture

Posted by , on 21 July 2026

In this highlight, we hear from Juan C. Landoni, who discusses his recent work uncovering how mitochondria distribute their genome through pearling (Landoni et al. 2026, Science), and the key role of mitochondrial trafficking in maintaining new material dissemination and network architecture (Winter, Landoni et al. 2026, JCB).
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Compartmentalized Cytoplasmic Tradewinds

Posted by , on 9 July 2026

Cathy Galbraith and Jim Galbraith share their story of answering how does a cell deliver a soluble protein — untethered to any motor, riding on no track — to the right place at the right time? They used six different imaging approaches to discover hidden cytoplasmic compartments and tradewinds that were hiding in plain sight.
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Imaging spotlight: VLab4Mic

Posted by , on 7 July 2026

In this preprint highlight, Damián Martínez, Bruno M. Saraiva, Mario Del Rosario, Ricardo Henriques introduce VLab4Mic, an open-source simulation platform that allows researchers to optimise microscopy experiments before performing them.
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