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JCS snapshot – Cytotoxic T lymphocytes adapt to the loss of Cdc42

Posted by , on 10 September 2025

In our latest JCS snapshot, we hear from Adam Rochussen who, together with Gillian Griffiths and Claire Ma, discovered that cytotoxic T lymphocytes are able to adapt to the loss of the key polarity factor Cdc42. In this snapshot, Adam takes us through the key findings from their research.

Research Highlight: https://journals.biologists.com/jcs/article/138/15/e138_e1502/368799/Cytotoxic-T-lymphocytes-adapt-to-loss-of-a-key

Research Article: https://journals.biologists.com/jcs/article/138/15/jcs263826/368784/Transcriptional-adaptation-after-deletion-of-Cdc42

First person interview: https://journals.biologists.com/jcs/article/138/15/jcs264258/368781/First-person-Adam-Rochussen

For more JCS snapshots, and for other video content from The Company of Biologists, follow our YouTube channel: https://www.youtube.com/@CompanyofBiologists/featured

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