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JCS snapshot: Suppressing microtubule detyrosination augments AAV2 endosomal escape & gene delivery

Posted by , on 19 February 2026

In our latest JCS snapshot we hear from Shefali Tripathi, who, together with Nitin Mohan, Giridhara Jayandharan and team, found that suppressing microtubule detyrosination augments adeno-associated virus 2 endosomal escape and gene delivery. In this snapshot, Shefali takes us through the key findings from their research.

Research Article: https://journals.biologists.com/jcs/article/138/23/jcs264190/370043/Suppressing-microtubule-detyrosination-augments

First person interview: https://journals.biologists.com/jcs/article/138/23/jcs264542/370042/First-person-Shefali-Tripathi

For more JCS snapshots: https://focalplane.biologists.com/tag/jcs-snapshots/

For video content from The Company of Biologists, follow our YouTube channel: https://www.youtube.com/@CompanyofBiologists/featured

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