JCS snapshot – Cytotoxic T lymphocytes adapt to the loss of Cdc42
Posted by FocalPlane, on 10 September 2025
In our latest JCS snapshot, we hear from Adam Rochussen who, together with Gillian Griffiths and Claire Ma, discovered that cytotoxic T lymphocytes are able to adapt to the loss of the key polarity factor Cdc42. In this snapshot, Adam takes us through the key findings from their research.
Research Highlight: https://journals.biologists.com/jcs/article/138/15/e138_e1502/368799/Cytotoxic-T-lymphocytes-adapt-to-loss-of-a-key
Research Article: https://journals.biologists.com/jcs/article/138/15/jcs263826/368784/Transcriptional-adaptation-after-deletion-of-Cdc42
First person interview: https://journals.biologists.com/jcs/article/138/15/jcs264258/368781/First-person-Adam-Rochussen
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